C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: proliferating cell nuclear antigen
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000132646 PCNA 9606 - 20:5114953-5126626 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000379143 PCNA-001 5114953-5120026 protein_coding
  ENST00000379160 PCNA-002 5114953-5126626 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000379143ENST00000379160
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000379143 9.777±0.00 20.969±0.00 N/A 7.845±2.07 11.019±0.55 12.652±1.59 7.406±0.00 15.497±9.25 6.043±0.73 5.552±0.00 4.111±1.05 47.770±43.79 40.108±4.92 45.300±9.44
ENST00000379160 1.602±0.00 N/A 2.753±0.00 N/A 2.077±0.00 1.584±0.00 2.210±0.47 N/A N/A 4.693±1.77 2.537±0.00 13.783±11.04 N/A 6.402±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003M9 CIL_0003M9_0001 CGP 20:5068232-5126626
CIL_0004G1 CIL_0004G1_0001 CGP 20:5114953-5197887

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000077 IEA DNA damage checkpoint
GO:0000082 TAS G1/S transition of mitotic cell cycle
GO:0000083 TAS regulation of transcription involved in G1/S transition of mitotic cell cycle
GO:0000278 TAS mitotic cell cycle
GO:0000701 IDA purine-specific mismatch base pair DNA N-glycosylase activity
GO:0000722 TAS telomere maintenance via recombination
GO:0000723 TAS telomere maintenance
GO:0003677 IEA DNA binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005663 TAS DNA replication factor C complex
GO:0005737 IDA cytoplasm
GO:0005813 IDA centrosome
GO:0006271 TAS DNA strand elongation involved in DNA replication
GO:0006272 IBA leading strand elongation
GO:0006275 IEA regulation of DNA replication
GO:0006281 TAS DNA repair
GO:0006283 TAS transcription-coupled nucleotide-excision repair
GO:0006284 TAS base-excision repair
GO:0006289 TAS nucleotide-excision repair
GO:0006297 TAS nucleotide-excision repair, DNA gap filling
GO:0006298 IDA mismatch repair
GO:0007507 IEA heart development
GO:0008283 TAS cell proliferation
GO:0019985 IDA translesion synthesis
GO:0030337 IEA DNA polymerase processivity factor activity
GO:0030855 IEP epithelial cell differentiation
GO:0030896 IEA checkpoint clamp complex
GO:0030971 IPI receptor tyrosine kinase binding
GO:0032077 IDA positive regulation of deoxyribonuclease activity
GO:0032139 IDA dinucleotide insertion or deletion binding
GO:0032201 TAS telomere maintenance via semi-conservative replication
GO:0032405 IDA MutLalpha complex binding
GO:0033993 IEA response to lipid
GO:0042802 IPI identical protein binding
GO:0043596 IDA nuclear replication fork
GO:0043626 IBA PCNA complex
GO:0046686 IEA response to cadmium ion
GO:0070062 IDA extracellular vesicular exosome
GO:0070182 IPI DNA polymerase binding
GO:0070557 IDA PCNA-p21 complex

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000054155 pcna proliferating cell nuclear antigen protein_coding Danio_rerio
ENSMUSG00000027342 Pcna proliferating cell nuclear antigen protein_coding Mus_musculus
ENSMUSG00000067608 Pcna-ps2 proliferating cell nuclear antigen pseudogene 2 protein_coding Mus_musculus

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