C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cholinergic receptor, muscarinic 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000133019 CHRM3 9606 + 1:239386565-239915452 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000255380 CHRM3-001 239629073-239915452 protein_coding
  ENST00000448020 CHRM3-002 239719543-239907780 protein_coding
  ENST00000468573 CHRM3-004 239386565-239886596 processed_transcript
  ENST00000481779 CHRM3-005 239408220-239546612 processed_transcript
  ENST00000487470 CHRM3-003 239632251-239703649 processed_transcript
  ENST00000492335 CHRM3-006 239386920-239606207 processed_transcript
  ENST00000615928 CHRM3-201 239632206-239909415 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000255380ENST00000468573ENST00000481779ENST00000492335ENST00000615928
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000255380 0.194±0.00 0.141±0.00 0.280±0.00 2.006±0.40 0.199±0.03 0.509±0.20 0.019±0.01 0.078±0.07 1.569±1.52 0.091±0.02 0.021±0.00 0.844±0.45 0.124±0.02 0.250±0.00
ENST00000468573 N/A N/A N/A N/A 0.259±0.00 N/A 0.063±0.00 0.132±0.00 3.346±0.00 N/A N/A 1.237±0.49 0.094±0.00 N/A
ENST00000481779 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.132±0.00 N/A N/A N/A
ENST00000492335 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.726±0.00 N/A N/A
ENST00000615928 N/A N/A N/A N/A 0.351±0.00 N/A 0.046±0.00 N/A N/A 0.260±0.00 0.075±0.04 N/A 0.347±0.11 1.311±0.06

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003056 IEA regulation of vascular smooth muscle contraction
GO:0004435 TAS phosphatidylinositol phospholipase C activity
GO:0004872 TAS receptor activity
GO:0004930 IEA G-protein coupled receptor activity
GO:0005515 IPI protein binding
GO:0005886 TAS plasma membrane
GO:0005887 IEA:ISS integral component of plasma membrane
GO:0006112 TAS energy reserve metabolic process
GO:0006464 TAS cellular protein modification process
GO:0006939 IEA smooth muscle contraction
GO:0007165 TAS signal transduction
GO:0007186 TAS:IEA G-protein coupled receptor signaling pathway
GO:0007213 ISS G-protein coupled acetylcholine receptor signaling pathway
GO:0007399 TAS nervous system development
GO:0007586 IEA digestion
GO:0008144 IEA drug binding
GO:0008283 TAS cell proliferation
GO:0016021 IEA integral component of membrane
GO:0016907 ISS G-protein coupled acetylcholine receptor activity
GO:0019229 IEA regulation of vasoconstriction
GO:0030054 IEA cell junction
GO:0030425 IEA dendrite
GO:0032279 IEA asymmetric synapse
GO:0042166 ISS acetylcholine binding
GO:0043679 IEA axon terminus
GO:0044281 TAS small molecule metabolic process
GO:0045211 IEA postsynaptic membrane
GO:0045987 IEA positive regulation of smooth muscle contraction
GO:0046541 IEA saliva secretion
GO:0050796 TAS regulation of insulin secretion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000071091 chrm3a cholinergic receptor, muscarinic 3a protein_coding Danio_rerio
ENSDARG00000071298 chrm3b cholinergic receptor, muscarinic 3b protein_coding Danio_rerio
ENSMUSG00000046159 Chrm3 cholinergic receptor, muscarinic 3, cardiac protein_coding Mus_musculus

Loading