C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: cholinergic receptor, muscarinic 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000255380 CHRM3-001 ENSG00000133019 9606 + 1:239629073-239915452 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000255380
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000255380 0.194±0.00 0.141±0.00 0.280±0.00 2.006±0.40 0.199±0.03 0.509±0.20 0.019±0.01 0.078±0.07 1.569±1.52 0.091±0.02 0.021±0.00 0.844±0.45 0.124±0.02 0.250±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003056 IEA regulation of vascular smooth muscle contraction
GO:0004435 TAS phosphatidylinositol phospholipase C activity
GO:0004872 TAS receptor activity
GO:0004930 IEA G-protein coupled receptor activity
GO:0005515 IPI protein binding
GO:0005886 TAS plasma membrane
GO:0005887 IEA:ISS integral component of plasma membrane
GO:0006112 TAS energy reserve metabolic process
GO:0006464 TAS cellular protein modification process
GO:0006939 IEA smooth muscle contraction
GO:0007165 TAS signal transduction
GO:0007186 TAS:IEA G-protein coupled receptor signaling pathway
GO:0007213 ISS G-protein coupled acetylcholine receptor signaling pathway
GO:0007399 TAS nervous system development
GO:0007586 IEA digestion
GO:0008144 IEA drug binding
GO:0008283 TAS cell proliferation
GO:0016021 IEA integral component of membrane
GO:0016907 ISS G-protein coupled acetylcholine receptor activity
GO:0019229 IEA regulation of vasoconstriction
GO:0030054 IEA cell junction
GO:0030425 IEA dendrite
GO:0032279 IEA asymmetric synapse
GO:0042166 ISS acetylcholine binding
GO:0043679 IEA axon terminus
GO:0044281 TAS small molecule metabolic process
GO:0045211 IEA postsynaptic membrane
GO:0045987 IEA positive regulation of smooth muscle contraction
GO:0046541 IEA saliva secretion
GO:0050796 TAS regulation of insulin secretion

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000187510 Chrm3-001 protein_coding Mus_musculus 0 2278
ENSMUST00000063093 Chrm3-201 protein_coding Mus_musculus 0 1997
ENSDART00000077955 chrm2a-001 protein_coding Danio_rerio 6e-19 102

Loading