C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: mediator complex subunit 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000133997 MED6 9606 - 14:70581257-70600690 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000256379 MED6-001 70583589-70600667 protein_coding
  ENST00000430055 MED6-004 70584086-70600655 protein_coding
  ENST00000440435 MED6-002 70584525-70600655 protein_coding
  ENST00000553523 MED6-011 70596212-70597830 retained_intron
  ENST00000553611 MED6-006 70591266-70600666 retained_intron
  ENST00000554870 MED6-003 70592578-70600655 retained_intron
  ENST00000554963 MED6-012 70581257-70600643 protein_coding
  ENST00000555296 MED6-010 70584665-70591814 retained_intron
  ENST00000556044 MED6-007 70591288-70600653 processed_transcript
  ENST00000556423 MED6-008 70596212-70600653 retained_intron
  ENST00000556495 MED6-005 70592511-70600664 retained_intron
  ENST00000615788 MED6-201 70583221-70600690 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000256379ENST00000430055ENST00000440435ENST00000553611ENST00000554870ENST00000554963ENST00000555296ENST00000556044ENST00000556423ENST00000556495ENST00000615788
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000256379 N/A N/A N/A 1.257±0.00 0.618±0.00 N/A 0.528±0.00 N/A 0.820±0.00 N/A N/A 1.896±0.40 1.477±0.05 2.073±0.36
ENST00000430055 1.152±0.00 4.891±0.00 N/A 2.501±0.52 2.591±0.58 1.461±0.10 3.329±0.00 2.268±0.99 1.713±0.44 2.138±0.80 3.058±0.67 2.532±0.63 5.182±1.64 4.044±0.05
ENST00000440435 2.377±0.00 6.562±0.00 0.836±0.00 3.855±0.00 3.201±0.00 2.394±0.00 N/A 1.617±0.00 1.957±0.00 2.615±0.23 3.221±0.00 8.019±0.00 10.073±0.00 6.123±2.15
ENST00000553611 N/A N/A 2.968±0.00 N/A 8.384±0.00 N/A N/A N/A 5.182±0.00 6.850±0.00 3.870±0.00 13.443±0.00 N/A N/A
ENST00000554870 N/A N/A 0.921±0.00 N/A N/A 2.040±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000554963 N/A N/A N/A 2.225±0.17 2.591±0.20 1.841±0.00 1.148±0.26 1.778±0.00 2.529±0.00 N/A 4.350±0.00 2.447±0.00 2.395±0.00 3.651±0.00
ENST00000555296 N/A N/A 0.804±0.00 N/A N/A N/A N/A N/A 1.526±0.00 N/A N/A N/A N/A N/A
ENST00000556044 2.586±0.00 N/A 2.631±0.00 18.706±0.00 N/A 6.143±0.00 2.282±0.00 5.468±0.00 N/A 3.735±0.00 N/A 16.383±0.00 N/A N/A
ENST00000556423 N/A N/A N/A N/A N/A N/A 1.370±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000556495 N/A N/A N/A N/A N/A N/A N/A N/A 4.376±0.00 N/A N/A 5.098±0.00 N/A N/A
ENST00000615788 N/A N/A N/A N/A N/A 0.932±0.25 N/A N/A N/A N/A 0.676±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002WZ CIL_0002WZ_0002 CGP 14:70581257-70675360

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001104 IEA RNA polymerase II transcription cofactor activity
GO:0003677 IEA DNA binding
GO:0003713 IDA transcription coactivator activity
GO:0005515 IEA protein binding
GO:0005634 TAS nucleus
GO:0005654 TAS nucleoplasm
GO:0006357 TAS:IEA regulation of transcription from RNA polymerase II promoter
GO:0006366 IEA transcription from RNA polymerase II promoter
GO:0006367 TAS transcription initiation from RNA polymerase II promoter
GO:0008134 IPI transcription factor binding
GO:0010467 TAS gene expression
GO:0016020 IDA membrane
GO:0016592 IDA:IEA mediator complex
GO:0019827 IEA stem cell maintenance
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000034734 med6 mediator complex subunit 6 protein_coding Danio_rerio
ENSMUSG00000002679 Med6 mediator complex subunit 6 protein_coding Mus_musculus

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