C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: basic helix-loop-helix family, member e40
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000134107 BHLHE40 9606 + 3:4979116-4985323 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000256495 BHLHE40-001 4979116-4985323 protein_coding
  ENST00000460806 BHLHE40-003 4980232-4981610 retained_intron
  ENST00000467610 BHLHE40-002 4979437-4983268 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000256495ENST00000467610
Transcript ID Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000256495 6.437±0.00 9.367±0.00 15.642±0.00 1.620±0.00 5.136±3.31 19.789±11.11 21.667±7.98 9.552±0.53 3.298±0.25 53.746±29.02 20.012±7.16 4.020±0.00
ENST00000467610 4.582±0.00 N/A 6.298±0.00 N/A 0.766±0.00 N/A N/A N/A 9.212±0.00 N/A N/A 2.537±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00050D CIL_00050D_0001 CGP 3:4493348-4985323
CIL_00050C CIL_00050C_0001 CGP 3:4979116-5180912

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000981 IDA sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001078 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0001102 ISS RNA polymerase II activating transcription factor binding
GO:0001191 IDA RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription
GO:0003677 IEA DNA binding
GO:0003700 NAS sequence-specific DNA binding transcription factor activity
GO:0003705 ISS RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0003714 IDA transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005730 IDA nucleolus
GO:0005794 IDA Golgi apparatus
GO:0006355 NAS:IEA regulation of transcription, DNA-templated
GO:0006366 ISS transcription from RNA polymerase II promoter
GO:0007623 IEA circadian rhythm
GO:0009416 IEA response to light stimulus
GO:0019904 IPI protein domain specific binding
GO:0032922 IDA circadian regulation of gene expression
GO:0042803 IDA protein homodimerization activity
GO:0043153 ISS entrainment of circadian clock by photoperiod
GO:0043425 IPI bHLH transcription factor binding
GO:0043426 ISS MRF binding
GO:0043433 IDA negative regulation of sequence-specific DNA binding transcription factor activity
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0046982 IPI protein heterodimerization activity
GO:0046983 IEA protein dimerization activity
GO:0070888 IDA E-box binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000004060 bhlhe40 basic helix-loop-helix family, member e40 protein_coding Danio_rerio
ENSMUSG00000030103 Bhlhe40 basic helix-loop-helix family, member e40 protein_coding Mus_musculus

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