C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: RAS-like, estrogen-regulated, growth inhibitor
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000134533 RERG 9606 - 12:15107783-15348675 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000256953 RERG-001 15107783-15221417 protein_coding
  ENST00000393736 RERG-007 15121065-15348598 protein_coding
  ENST00000437578 RERG-008 15346477-15348675 processed_transcript
  ENST00000536465 RERG-005 15107817-15218051 protein_coding
  ENST00000537647 RERG-010 15110927-15221406 protein_coding
  ENST00000537717 RERG-006 15217096-15221268 retained_intron
  ENST00000538313 RERG-002 15107790-15217629 protein_coding
  ENST00000545567 RERG-009 15109409-15138163 protein_coding
  ENST00000546331 RERG-004 15108607-15221417 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000256953ENST00000537647ENST00000537717ENST00000538313ENST00000546331
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000256953 4.580±0.00 12.086±0.00 3.202±0.00 3.123±0.08 5.670±2.71 9.050±6.46 0.863±0.55 8.971±8.82 6.046±0.00 5.008±0.02 1.038±0.00 6.014±4.92 7.420±2.60 9.465±8.33
ENST00000537647 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.482±0.00 2.699±0.00 N/A
ENST00000537717 N/A N/A 47.325±0.00 15.164±0.00 13.463±0.00 8.405±0.00 2.300±0.00 2.851±0.00 28.779±0.00 23.651±0.00 3.388±0.00 N/A N/A N/A
ENST00000538313 N/A N/A N/A N/A N/A N/A 0.390±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000546331 1.789±0.00 N/A 2.676±0.00 N/A N/A N/A 0.774±0.00 0.613±0.00 2.700±0.00 1.413±0.00 0.360±0.00 0.314±0.00 N/A 1.070±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000374 CIL_000374_0001 CGP 12:14973022-15348675
CIL_000375 CIL_000375_0001 CGP 12:15107783-15597399

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003924 IDA GTPase activity
GO:0005525 IEA GTP binding
GO:0005622 IEA intracellular
GO:0005634 IDA nucleus
GO:0005829 IDA cytosol
GO:0006184 IEA GTP catabolic process
GO:0007165 IEA signal transduction
GO:0007264 IEA:NAS small GTPase mediated signal transduction
GO:0008285 IDA negative regulation of cell proliferation
GO:0009725 IDA response to hormone
GO:0015031 IEA protein transport
GO:0016020 IEA membrane
GO:0019003 TAS GDP binding
GO:0030308 IDA negative regulation of cell growth
GO:0030331 NAS estrogen receptor binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000041104 CU694368.1 Uncharacterized protein protein_coding Danio_rerio
ENSMUSG00000030222 Rerg RAS-like, estrogen-regulated, growth-inhibitor protein_coding Mus_musculus

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