C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: damage-specific DNA binding protein 2, 48kDa
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000134574 DDB2 9606 + 11:47214465-47239240 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000256996 DDB2-001 47214942-47239240 protein_coding
  ENST00000378600 DDB2-006 47215137-47238849 protein_coding
  ENST00000378601 DDB2-002 47214992-47239189 nonsense_mediated_decay
  ENST00000378603 DDB2-007 47215137-47238849 protein_coding
  ENST00000610805 DDB2-014 47215088-47232959 nonsense_mediated_decay
  ENST00000612309 DDB2-003 47215095-47239217 retained_intron
  ENST00000614394 DDB2-010 47234581-47236087 retained_intron
  ENST00000614825 DDB2-012 47214570-47234653 protein_coding
  ENST00000614884 DDB2-016 47237806-47239217 retained_intron
  ENST00000615695 DDB2-015 47215058-47217411 retained_intron
  ENST00000616278 DDB2-004 47215137-47238849 nonsense_mediated_decay
  ENST00000617022 DDB2-005 47215112-47239216 retained_intron
  ENST00000617847 DDB2-008 47216913-47239191 nonsense_mediated_decay
  ENST00000620515 DDB2-009 47234627-47237900 processed_transcript
  ENST00000622090 DDB2-013 47215045-47232836 protein_coding
  ENST00000622878 DDB2-011 47214465-47216873 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainBreastColonHeartLiverLungMuscleOvaryPlacentaTestisENST00000256996ENST00000378600ENST00000378601ENST00000612309ENST00000614394ENST00000614884ENST00000615695ENST00000617022ENST00000617847
Transcript ID Adipose Brain Breast Colon Heart Liver Lung Muscle Ovary Placenta Testis
ENST00000256996 5.413±0.00 N/A 6.453±0.00 2.451±0.00 0.668±0.51 N/A 1.444±0.00 1.885±0.00 4.559±4.28 4.293±2.36 N/A
ENST00000378600 N/A N/A N/A N/A N/A N/A N/A 1.947±0.00 N/A N/A N/A
ENST00000378601 N/A N/A N/A N/A 1.760±0.00 N/A 3.083±0.00 1.180±0.00 1.706±0.41 2.302±0.00 2.450±0.00
ENST00000612309 1.381±0.00 N/A 1.818±0.00 N/A 0.341±0.07 1.183±0.00 1.131±0.09 N/A 1.492±0.27 1.280±0.00 1.483±0.00
ENST00000614394 N/A 1.947±0.00 N/A 1.877±0.00 1.037±0.00 N/A 2.449±0.00 N/A 2.842±1.97 6.819±0.00 10.256±0.00
ENST00000614884 5.173±0.00 1.000±0.00 7.788±0.00 3.869±0.00 N/A N/A 5.364±0.00 2.763±0.00 8.636±0.00 3.073±0.00 N/A
ENST00000615695 N/A N/A N/A N/A 0.434±0.00 N/A N/A N/A N/A N/A N/A
ENST00000617022 N/A N/A N/A N/A 0.125±0.00 N/A N/A N/A 0.571±0.00 N/A N/A
ENST00000617847 N/A N/A N/A 0.707±0.00 N/A N/A N/A N/A 1.192±0.00 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000209 IDA protein polyubiquitination
GO:0000718 TAS nucleotide-excision repair, DNA damage removal
GO:0003677 TAS DNA binding
GO:0003684 IDA damaged DNA binding
GO:0003824 IEA catalytic activity
GO:0004842 IDA ubiquitin-protein transferase activity
GO:0005515 IPI:IEA protein binding
GO:0005654 TAS nucleoplasm
GO:0006281 TAS DNA repair
GO:0006289 TAS nucleotide-excision repair
GO:0006290 IEA pyrimidine dimer repair
GO:0009411 IDA response to UV
GO:0031465 IDA Cul4B-RING E3 ubiquitin ligase complex
GO:0035518 IDA histone H2A monoubiquitination
GO:0043234 IDA protein complex
GO:0051865 IDA protein autoubiquitination
GO:0070914 IDA UV-damage excision repair

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000041140 ddb2 damage-specific DNA binding protein 2 protein_coding Danio_rerio
ENSMUSG00000002109 Ddb2 damage specific DNA binding protein 2 protein_coding Mus_musculus

Loading