C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: excision repair cross-complementation group 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000134899 ERCC5 9606 + 13:102844844-102876001 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000355739 ERCC5-001 102844844-102876001 protein_coding
  ENST00000375954 ERCC5-006 102864718-102875983 protein_coding
  ENST00000375958 ERCC5-003 102846112-102853933 retained_intron
  ENST00000472151 ERCC5-002 102846049-102853872 nonsense_mediated_decay
  ENST00000472247 ERCC5-005 102874735-102875892 processed_transcript
  ENST00000481099 ERCC5-004 102865943-102868257 retained_intron
  ENST00000535557 ERCC5-201 102845841-102858937 protein_coding
  ENST00000610537 ERCC5-202 102846257-102875995 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000472247ENST00000535557ENST00000610537
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000472247 N/A 24.167±0.00 N/A N/A N/A N/A N/A 6.907±0.00 N/A N/A N/A N/A 13.337±0.00
ENST00000535557 N/A N/A N/A N/A N/A 1.810±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000610537 13.625±0.00 13.709±0.00 5.417±1.56 8.760±3.36 6.736±0.98 2.670±2.14 6.270±0.82 3.814±0.38 8.159±0.16 4.352±2.75 10.608±5.12 7.262±2.76 14.114±3.98

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000WF CIL_0000WF_0001 CGP 13:102799049-102872398

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000405 IDA bubble DNA binding
GO:0000718 TAS nucleotide-excision repair, DNA damage removal
GO:0000737 IDA DNA catabolic process, endonucleolytic
GO:0003677 IEA DNA binding
GO:0003690 IDA double-stranded DNA binding
GO:0003697 IDA:IEA single-stranded DNA binding
GO:0003824 IEA catalytic activity
GO:0004518 IEA nuclease activity
GO:0004519 TAS:IEA endonuclease activity
GO:0004520 IDA endodeoxyribonuclease activity
GO:0005515 IPI protein binding
GO:0005634 IDA:IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0005662 IDA DNA replication factor A complex
GO:0005675 IDA holo TFIIH complex
GO:0006281 TAS:IEA DNA repair
GO:0006283 IMP transcription-coupled nucleotide-excision repair
GO:0006289 TAS:IEA nucleotide-excision repair
GO:0006295 IMP nucleotide-excision repair, DNA incision, 3'-to lesion
GO:0009411 IMP response to UV
GO:0009650 IGI UV protection
GO:0010225 IMP response to UV-C
GO:0016591 IDA DNA-directed RNA polymerase II, holoenzyme
GO:0042803 IPI protein homodimerization activity
GO:0043066 IMP negative regulation of apoptotic process
GO:0045111 IDA intermediate filament cytoskeleton
GO:0046872 IEA metal ion binding
GO:0047485 IPI protein N-terminus binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000023678 ercc5 excision repair cross-complementing rodent repair deficiency, complementation group 5 (xeroderma pigmentosum, complementation gr protein_coding Danio_rerio
ENSMUSG00000026048 Ercc5 excision repair cross-complementing rodent repair deficiency, complementation group 5 protein_coding Mus_musculus

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