C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000135439 AGAP2 9606 - 12:57723761-57742157 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000257897 AGAP2-001 57723761-57742157 protein_coding
  ENST00000328568 AGAP2-003 57725197-57737836 protein_coding
  ENST00000547588 AGAP2-002 57726552-57738246 protein_coding
  ENST00000549129 AGAP2-005 57730383-57731829 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainLungENST00000257897ENST00000328568ENST00000547588
Transcript ID Brain Lung
ENST00000257897 N/A 1.049±0.00
ENST00000328568 46.061±42.48 N/A
ENST00000547588 4.181±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002KQ CIL_0002KQ_0002 CGP 12:57723761-57750211

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI:IEA protein binding
GO:0005525 IEA GTP binding
GO:0005622 IEA intracellular
GO:0005634 IDA nucleus
GO:0005730 IDA nucleolus
GO:0005739 IDA mitochondrion
GO:0006184 IEA GTP catabolic process
GO:0007165 IEA signal transduction
GO:0007264 IEA small GTPase mediated signal transduction
GO:0007411 TAS axon guidance
GO:0008060 IEA ARF GTPase activator activity
GO:0008270 IEA zinc ion binding
GO:0014068 IEA positive regulation of phosphatidylinositol 3-kinase signaling
GO:0015031 IEA protein transport
GO:0016020 IDA:IEA membrane
GO:0019901 IEA protein kinase binding
GO:0030295 IEA protein kinase activator activity
GO:0032312 IEA regulation of ARF GTPase activity
GO:0033601 IEA positive regulation of mammary gland epithelial cell proliferation
GO:0042177 IDA negative regulation of protein catabolic process
GO:0043066 IEA negative regulation of apoptotic process
GO:0043524 IGI negative regulation of neuron apoptotic process
GO:0043547 IEA positive regulation of GTPase activity
GO:0045860 IEA positive regulation of protein kinase activity
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0046427 IEA positive regulation of JAK-STAT cascade
GO:0060749 IEA mammary gland alveolus development
GO:2001240 IEA negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000061117 agap2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 protein_coding Danio_rerio
ENSMUSG00000025422 Agap2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 protein_coding Mus_musculus

Loading