C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info

Description: ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000547588 AGAP2-002 ENSG00000135439 9606 - 12:57726552-57738246 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainENST00000547588
Transcript ID Brain
ENST00000547588 4.181±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002KQ CIL_0002KQ_0002 CGP 12:57723761-57750211

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005515 IEA protein binding
GO:0005525 IEA GTP binding
GO:0005622 IEA intracellular
GO:0005634 IDA nucleus
GO:0005730 IDA nucleolus
GO:0005739 IDA mitochondrion
GO:0006184 IEA GTP catabolic process
GO:0007165 IEA signal transduction
GO:0007264 IEA small GTPase mediated signal transduction
GO:0008060 IEA ARF GTPase activator activity
GO:0008270 IEA zinc ion binding
GO:0014068 IEA positive regulation of phosphatidylinositol 3-kinase signaling
GO:0015031 IEA protein transport
GO:0016020 IEA membrane
GO:0019901 IEA protein kinase binding
GO:0030295 IEA protein kinase activator activity
GO:0032312 IEA regulation of ARF GTPase activity
GO:0033601 IEA positive regulation of mammary gland epithelial cell proliferation
GO:0043066 IEA negative regulation of apoptotic process
GO:0043524 IEA negative regulation of neuron apoptotic process
GO:0043547 IEA positive regulation of GTPase activity
GO:0045860 IEA positive regulation of protein kinase activity
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0046427 IEA positive regulation of JAK-STAT cascade
GO:0060749 IEA mammary gland alveolus development
GO:2001240 IEA negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000039259 Agap2-201 protein_coding Mus_musculus 0 4588

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