C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: tubulin tyrosine ligase-like family, member 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000135912 TTLL4 9606 + 2:218710845-218755416 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000258398 TTLL4-201 218737574-218755416 protein_coding
  ENST00000392102 TTLL4-001 218710875-218755416 protein_coding
  ENST00000415717 TTLL4-006 218710849-218737979 protein_coding
  ENST00000417196 TTLL4-018 218745117-218748897 nonsense_mediated_decay
  ENST00000417855 TTLL4-016 218751754-218754416 protein_coding
  ENST00000424644 TTLL4-008 218710994-218737978 protein_coding
  ENST00000434241 TTLL4-019 218746155-218748919 nonsense_mediated_decay
  ENST00000436668 TTLL4-015 218748902-218754220 protein_coding
  ENST00000437755 TTLL4-007 218710912-218738199 protein_coding
  ENST00000442769 TTLL4-003 218710956-218754693 protein_coding
  ENST00000448224 TTLL4-020 218747034-218749363 protein_coding
  ENST00000457313 TTLL4-002 218710845-218754693 protein_coding
  ENST00000461181 TTLL4-009 218745387-218746329 retained_intron
  ENST00000465558 TTLL4-005 218746151-218753354 retained_intron
  ENST00000467841 TTLL4-011 218745995-218749362 retained_intron
  ENST00000472527 TTLL4-017 218753098-218754503 retained_intron
  ENST00000475950 TTLL4-013 218746132-218747584 retained_intron
  ENST00000480472 TTLL4-012 218746096-218749282 retained_intron
  ENST00000480929 TTLL4-004 218746139-218748654 retained_intron
  ENST00000491899 TTLL4-014 218746761-218747668 retained_intron
  ENST00000494428 TTLL4-010 218745553-218748203 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000258398ENST00000392102ENST00000417196ENST00000434241ENST00000436668ENST00000437755ENST00000442769ENST00000457313ENST00000461181ENST00000465558ENST00000472527ENST00000480929ENST00000491899
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000258398 N/A N/A N/A 0.385±0.00 N/A N/A N/A 0.918±0.00 0.293±0.00 N/A N/A 2.490±0.54 N/A 4.057±0.14
ENST00000392102 N/A 0.457±0.00 N/A N/A 0.291±0.00 0.583±0.00 N/A 0.578±0.00 N/A N/A 0.313±0.00 1.604±0.00 0.757±0.08 N/A
ENST00000417196 N/A N/A N/A N/A 0.905±0.00 1.473±0.00 0.481±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000434241 N/A N/A N/A N/A N/A N/A N/A 1.390±0.00 N/A N/A N/A N/A N/A N/A
ENST00000436668 N/A N/A N/A 1.587±0.00 N/A N/A 0.536±0.00 3.120±0.00 N/A N/A 1.326±0.00 7.984±0.00 N/A N/A
ENST00000437755 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.194±0.00 N/A N/A N/A
ENST00000442769 0.751±0.00 N/A N/A 0.612±0.27 0.560±0.16 0.422±0.00 0.345±0.26 N/A N/A 1.983±0.00 0.721±0.49 3.149±2.14 1.767±1.03 7.213±2.04
ENST00000457313 0.560±0.00 0.805±0.00 0.149±0.00 N/A 0.450±0.22 N/A N/A 0.639±0.00 0.729±0.04 N/A N/A 2.455±1.49 1.926±0.22 7.124±2.58
ENST00000461181 N/A N/A 1.516±0.00 N/A 1.567±0.00 N/A 0.538±0.00 N/A 2.036±0.00 N/A N/A N/A N/A N/A
ENST00000465558 N/A N/A N/A 2.793±0.00 N/A N/A N/A N/A N/A 2.345±0.00 N/A N/A N/A N/A
ENST00000472527 N/A 3.641±0.00 N/A N/A N/A N/A 1.067±0.00 0.859±0.00 3.046±0.00 N/A 1.640±0.00 11.756±0.00 5.550±0.26 20.760±0.00
ENST00000480929 N/A N/A N/A N/A 0.478±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000491899 N/A N/A N/A N/A N/A N/A N/A 2.329±0.00 N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000652 CIL_000652_0001 CGP 2:218672026-218755416
CIL_000653 CIL_000653_0001 CGP 2:218710845-218815293

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005737 IEA cytoplasm
GO:0005856 IEA cytoskeleton
GO:0005929 IEA cilium
GO:0006464 IEA cellular protein modification process
GO:0015631 ISS tubulin binding
GO:0016874 IEA ligase activity
GO:0018095 ISS protein polyglutamylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000078935 ttll4 tubulin tyrosine ligase-like family, member 4 protein_coding Danio_rerio
ENSMUSG00000033257 Ttll4 tubulin tyrosine ligase-like family, member 4 protein_coding Mus_musculus

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