C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: integral membrane protein 2C
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000135916 ITM2C 9606 + 2:230864639-230879248 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000326407 ITM2C-006 230864980-230879248 protein_coding
  ENST00000326427 ITM2C-001 230864900-230879247 protein_coding
  ENST00000335005 ITM2C-002 230864948-230879247 protein_coding
  ENST00000409704 ITM2C-008 230865268-230878385 protein_coding
  ENST00000418408 ITM2C-009 230865664-230876967 protein_coding
  ENST00000457215 ITM2C-004 230864639-230876947 protein_coding
  ENST00000492029 ITM2C-005 230873231-230876967 processed_transcript
  ENST00000541852 ITM2C-010 230864654-230876967 protein_coding
  ENST00000543957 ITM2C-007 230865248-230876960 protein_coding
  ENST00000620962 ITM2C-201 230878218-230878718 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000326407ENST00000326427ENST00000335005ENST00000409704ENST00000457215ENST00000492029ENST00000620962
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000326407 N/A N/A 2.404±0.00 121.166±0.00 N/A 96.713±0.00 N/A N/A N/A N/A N/A 11.581±0.00 N/A 8.455±0.00
ENST00000326427 22.657±0.00 90.591±0.00 5.998±0.00 211.561±163.48 24.508±4.15 66.785±12.53 7.526±6.20 89.639±0.00 13.094±0.48 35.920±0.00 3.321±3.08 53.855±37.47 123.981±30.65 40.902±0.00
ENST00000335005 N/A N/A N/A N/A N/A 81.099±0.00 N/A N/A N/A 15.459±0.00 N/A 23.304±9.37 43.823±0.00 6.979±0.00
ENST00000409704 N/A N/A 5.514±0.00 N/A N/A N/A 2.249±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000457215 N/A N/A N/A N/A N/A N/A 0.938±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000492029 N/A N/A N/A N/A N/A 113.400±0.00 N/A 2.888±0.00 20.353±0.00 N/A 4.982±0.00 N/A N/A N/A
ENST00000620962 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.805±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004KY CIL_0004KY_0002 CGP 2:230712845-230879248

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001540 IPI beta-amyloid binding
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005764 ISS lysosome
GO:0005794 IDA Golgi apparatus
GO:0005886 IDA plasma membrane
GO:0010977 IDA negative regulation of neuron projection development
GO:0016021 IEA integral component of membrane
GO:0030182 ISS neuron differentiation
GO:0048471 IDA perinuclear region of cytoplasm
GO:0070062 IDA extracellular vesicular exosome
GO:2001238 IEA positive regulation of extrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000039650 itm2cb integral membrane protein 2Cb protein_coding Danio_rerio
ENSDARG00000043448 itm2ca integral membrane protein 2Ca protein_coding Danio_rerio
ENSMUSG00000026223 Itm2c integral membrane protein 2C protein_coding Mus_musculus

Loading