C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: integral membrane protein 2C
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000026223 Itm2c 10090 + 1:85894281-85908675 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000027425 Itm2c-001 85894281-85908675 protein_coding
  ENSMUST00000139837 Itm2c-002 85906161-85907791 retained_intron
  ENSMUST00000185569 Itm2c-003 85894619-85908359 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000027425ENSMUST00000185569
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000027425 127.425±53.07 283.614±29.68 77.417±0.46 68.132±16.01 91.003±7.46 65.310±9.24 41.213±2.00 69.201±4.31 25.663±6.06 120.678±5.09 14.573±0.86 169.031±48.30 32.266±14.02 15.130±8.00
ENSMUST00000185569 N/A 102.613±22.37 N/A 205.380±0.00 N/A N/A N/A N/A N/A N/A 3.202±0.00 66.421±0.00 19.388±12.54 3.536±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004KY CIL_0004KY_0003 CGP 1:85793441-85908675

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001540 IEA beta-amyloid binding
GO:0005515 IEA protein binding
GO:0005524 IDA ATP binding
GO:0005764 IDA lysosome
GO:0005794 IEA Golgi apparatus
GO:0005886 ISS plasma membrane
GO:0010977 IEA negative regulation of neuron projection development
GO:0016021 IEA integral component of membrane
GO:0048471 IEA perinuclear region of cytoplasm
GO:0070062 IEA extracellular vesicular exosome
GO:2001238 IMP positive regulation of extrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000039650 itm2cb integral membrane protein 2Cb protein_coding Danio_rerio
ENSDARG00000043448 itm2ca integral membrane protein 2Ca protein_coding Danio_rerio
ENSG00000135916 ITM2C integral membrane protein 2C protein_coding Homo_sapiens

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