C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: DnaJ (Hsp40) homolog, subfamily B, member 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000135924 DNAJB2 9606 + 2:219279267-219286900 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000336576 DNAJB2-001 219279267-219286900 protein_coding
  ENST00000392086 DNAJB2-002 219279344-219286898 protein_coding
  ENST00000392087 DNAJB2-019 219279465-219284838 protein_coding
  ENST00000421532 DNAJB2-009 219279366-219282105 protein_coding
  ENST00000425450 DNAJB2-008 219279342-219284696 protein_coding
  ENST00000439026 DNAJB2-012 219279517-219282929 protein_coding
  ENST00000442681 DNAJB2-011 219279516-219282852 protein_coding
  ENST00000463463 DNAJB2-015 219279920-219284828 processed_transcript
  ENST00000470530 DNAJB2-018 219285263-219286200 processed_transcript
  ENST00000472019 DNAJB2-007 219282742-219286839 retained_intron
  ENST00000473750 DNAJB2-006 219282698-219285196 retained_intron
  ENST00000476254 DNAJB2-017 219283064-219284874 retained_intron
  ENST00000477917 DNAJB2-005 219279367-219286895 retained_intron
  ENST00000480537 DNAJB2-003 219279367-219282660 retained_intron
  ENST00000481815 DNAJB2-013 219279588-219280693 retained_intron
  ENST00000482988 DNAJB2-010 219279369-219280170 retained_intron
  ENST00000485220 DNAJB2-014 219279906-219281373 retained_intron
  ENST00000487855 DNAJB2-016 219280613-219282665 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000336576ENST00000392086ENST00000425450ENST00000463463ENST00000472019ENST00000477917ENST00000482988
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000336576 5.917±0.00 5.624±0.00 2.053±0.00 15.124±8.06 4.136±3.49 N/A 3.708±0.00 5.348±0.00 1.403±0.21 7.666±0.00 4.096±0.00 12.177±5.27 5.879±1.27 11.933±0.00
ENST00000392086 29.459±0.00 20.942±0.00 1.424±0.00 83.770±61.01 19.023±16.58 27.169±23.82 9.496±8.15 26.923±23.68 7.598±5.37 19.556±18.03 17.569±8.47 30.953±28.87 29.076±8.96 65.240±7.26
ENST00000425450 N/A N/A 4.916±0.00 N/A N/A 2.347±0.00 3.553±0.00 N/A 3.146±0.00 N/A 10.173±0.00 2.418±0.00 N/A N/A
ENST00000463463 N/A N/A N/A N/A N/A N/A N/A 4.020±0.00 N/A N/A N/A N/A N/A N/A
ENST00000472019 N/A N/A 4.401±0.00 N/A N/A N/A 2.447±0.00 1.433±0.00 N/A 2.534±0.00 N/A 24.152±22.53 25.874±0.00 104.640±0.00
ENST00000477917 N/A N/A N/A N/A N/A 0.296±0.00 N/A N/A 0.373±0.00 0.731±0.00 N/A 0.276±0.00 N/A N/A
ENST00000482988 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.138±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000916 CIL_000916_0001 VISTA 2:219106772-219707284
CIL_0006NW CIL_0006NW_0001 CGP 2:219279267-219309648

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000502 IDA proteasome complex
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005829 IDA cytosol
GO:0006457 TAS protein folding
GO:0006986 TAS response to unfolded protein
GO:0008219 IEA cell death
GO:0008285 IGI negative regulation of cell proliferation
GO:0016234 IDA inclusion body
GO:0030308 IGI negative regulation of cell growth
GO:0030433 IDA ER-associated ubiquitin-dependent protein catabolic process
GO:0030544 IPI Hsp70 protein binding
GO:0031398 IDA positive regulation of protein ubiquitination
GO:0031593 IDA polyubiquitin binding
GO:0032436 IDA positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0042026 IDA protein refolding
GO:0051082 IDA unfolded protein binding
GO:0051087 IPI chaperone binding
GO:0070628 IDA proteasome binding
GO:0090084 IDA negative regulation of inclusion body assembly
GO:0090086 IDA negative regulation of protein deubiquitination

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000058644 dnajb2 DnaJ (Hsp40) homolog, subfamily B, member 2 protein_coding Danio_rerio
ENSMUSG00000026203 Dnajb2 DnaJ (Hsp40) homolog, subfamily B, member 2 protein_coding Mus_musculus

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