C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: DnaJ (Hsp40) homolog, subfamily B, member 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000026203 Dnajb2 10090 + 1:75236406-75245692 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000055223 Dnajb2-201 75236465-75244804 protein_coding
  ENSMUST00000082158 Dnajb2-202 75236465-75244804 protein_coding
  ENSMUST00000185403 Dnajb2-010 75236513-75245055 nonsense_mediated_decay
  ENSMUST00000185654 Dnajb2-007 75236614-75239333 protein_coding
  ENSMUST00000186600 Dnajb2-008 75236772-75237681 retained_intron
  ENSMUST00000187058 Dnajb2-004 75236556-75245690 protein_coding
  ENSMUST00000188290 Dnajb2-003 75236487-75245690 protein_coding
  ENSMUST00000188346 Dnajb2-002 75236469-75245692 protein_coding
  ENSMUST00000188628 Dnajb2-009 75237075-75237524 retained_intron
  ENSMUST00000188931 Dnajb2-001 75236406-75245688 protein_coding
  ENSMUST00000190379 Dnajb2-011 75238924-75240921 retained_intron
  ENSMUST00000190445 Dnajb2-012 75241409-75244927 nonsense_mediated_decay

Mus musculus EnsemblGRCm38

Genome
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Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000055223ENSMUST00000082158ENSMUST00000186600ENSMUST00000187058ENSMUST00000188290ENSMUST00000188346ENSMUST00000188931
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000055223 N/A 8.253±0.71 N/A N/A N/A N/A N/A N/A N/A N/A N/A 11.593±1.08 N/A N/A
ENSMUST00000082158 N/A 8.027±0.00 N/A N/A N/A 5.406±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000186600 N/A N/A N/A 100.011±0.00 N/A N/A N/A N/A N/A N/A N/A 54.470±0.00 57.079±0.56 250.308±0.00
ENSMUST00000187058 N/A N/A N/A N/A 10.063±0.00 N/A N/A N/A 3.521±0.72 N/A N/A N/A 3.235±0.37 N/A
ENSMUST00000188290 5.974±2.19 6.751±0.11 5.624±0.00 9.290±0.68 6.100±0.40 N/A 15.529±2.03 7.387±1.42 9.652±3.62 7.959±0.58 15.549±1.81 9.079±1.04 5.716±2.11 69.156±25.67
ENSMUST00000188346 N/A N/A 3.935±0.00 N/A 6.781±0.06 4.279±0.26 4.452±0.00 4.663±0.00 4.600±1.57 N/A N/A 10.755±2.99 4.867±1.02 7.456±0.00
ENSMUST00000188931 10.936±1.99 14.064±6.26 9.387±1.11 6.161±2.25 13.819±2.07 8.513±3.09 11.230±2.11 8.259±1.06 9.906±3.60 14.780±0.38 12.059±2.83 13.135±5.41 5.275±1.02 31.359±14.69

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000916 CIL_000916_0002 VISTA 1:75047166-75647630
CIL_0006NW CIL_0006NW_0002 CGP 1:75236406-75264502

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000502 IEA proteasome complex
GO:0005515 IEA protein binding
GO:0005634 IEA nucleus
GO:0005829 IEA cytosol
GO:0008285 ISS negative regulation of cell proliferation
GO:0016234 IEA inclusion body
GO:0030308 ISS negative regulation of cell growth
GO:0030433 IEA ER-associated ubiquitin-dependent protein catabolic process
GO:0030544 IEA Hsp70 protein binding
GO:0031398 IEA positive regulation of protein ubiquitination
GO:0031593 IEA polyubiquitin binding
GO:0032436 IEA positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0042026 IEA protein refolding
GO:0051082 IEA unfolded protein binding
GO:0051087 IEA chaperone binding
GO:0070628 IEA proteasome binding
GO:0090084 IEA negative regulation of inclusion body assembly
GO:0090086 IEA negative regulation of protein deubiquitination

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000058644 dnajb2 DnaJ (Hsp40) homolog, subfamily B, member 2 protein_coding Danio_rerio
ENSG00000135924 DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 protein_coding Homo_sapiens

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