C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cytochrome P450, family 27, subfamily A, polypeptide 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000135929 CYP27A1 9606 + 2:218781749-218815293 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000258415 CYP27A1-001 218781756-218815293 protein_coding
  ENST00000411688 CYP27A1-005 218805914-218813025 protein_coding
  ENST00000445971 CYP27A1-004 218782153-218814067 nonsense_mediated_decay
  ENST00000466602 CYP27A1-003 218782174-218814091 retained_intron
  ENST00000494263 CYP27A1-002 218781749-218815288 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000258415ENST00000411688ENST00000494263
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000258415 12.564±0.00 10.205±0.00 2.189±0.00 10.576±8.64 9.156±8.00 20.283±0.00 2.940±1.74 44.882±34.19 177.647±0.00 26.730±21.31 9.585±0.00 18.075±15.90 2.625±1.35 7.754±4.50
ENST00000411688 N/A N/A N/A N/A N/A N/A N/A N/A 1.068±0.00 N/A N/A 20.244±0.00 3.106±0.00 4.000±0.00
ENST00000494263 N/A N/A N/A N/A N/A 0.655±0.00 N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000653 CIL_000653_0001 CGP 2:218710845-218815293
CIL_00064U CIL_00064U_0001 CGP 2:218781749-218832086

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005506 IEA iron ion binding
GO:0005739 IEA mitochondrion
GO:0005740 IEA mitochondrial envelope
GO:0005743 IEA mitochondrial inner membrane
GO:0005759 TAS mitochondrial matrix
GO:0006699 TAS bile acid biosynthetic process
GO:0006805 TAS xenobiotic metabolic process
GO:0008203 IEA cholesterol metabolic process
GO:0008206 TAS bile acid metabolic process
GO:0008395 TAS steroid hydroxylase activity
GO:0016125 TAS sterol metabolic process
GO:0016705 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0020037 IEA heme binding
GO:0030343 IEA vitamin D3 25-hydroxylase activity
GO:0031073 IEA cholesterol 26-hydroxylase activity
GO:0036378 IEA calcitriol biosynthetic process from calciol
GO:0044281 TAS small molecule metabolic process
GO:0047749 IEA cholestanetriol 26-monooxygenase activity
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000033802 cyp27a7 cytochrome P450, family 27, subfamily A, polypeptide 7 protein_coding Danio_rerio
ENSDARG00000055159 cyp27a1.4 cytochrome P450, family 27, subfamily A, polypeptide 1, gene 4 protein_coding Danio_rerio
ENSDARG00000069186 cyp27a1.2 cytochrome P450, family 27, subfamily A, polypeptide 1, gene 2 protein_coding Danio_rerio
ENSDARG00000088013 CYP27A1 (4 of 4) cytochrome P450, family 27, subfamily A, polypeptide 1 protein_coding Danio_rerio
ENSMUSG00000026170 Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 protein_coding Mus_musculus

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