C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cytochrome P450, family 27, subfamily a, polypeptide 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000026170 Cyp27a1 10090 + 1:74713574-74737892 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000027356 Cyp27a1-001 74713574-74737892 protein_coding
  ENSMUST00000189083 Cyp27a1-003 74736809-74737823 retained_intron
  ENSMUST00000190781 Cyp27a1-002 74735351-74736716 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000027356ENSMUST00000189083ENSMUST00000190781
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000027356 12.528±0.88 2.644±0.60 18.150±6.05 0.530±0.47 5.988±0.59 5.930±1.37 3.341±1.11 8.638±1.37 60.235±56.37 6.323±0.71 38.047±8.47 4.849±2.23 1.257±0.91 1.963±0.21
ENSMUST00000189083 N/A N/A N/A 2.303±0.00 N/A N/A N/A N/A N/A N/A N/A 7.016±0.00 0.528±0.01 0.847±0.00
ENSMUST00000190781 N/A N/A 21.820±0.00 N/A N/A N/A N/A N/A 8.625±1.31 N/A 24.333±0.00 10.542±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000653 CIL_000653_0002 CGP 1:74661745-74737892
CIL_00064U CIL_00064U_0002 CGP 1:74713574-74749221

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005506 IEA iron ion binding
GO:0005739 IDA mitochondrion
GO:0005740 IEA mitochondrial envelope
GO:0005743 IDA mitochondrial inner membrane
GO:0008203 IEA cholesterol metabolic process
GO:0020037 IEA heme binding
GO:0030343 IEA vitamin D3 25-hydroxylase activity
GO:0031073 IEA cholesterol 26-hydroxylase activity
GO:0036378 IEA calcitriol biosynthetic process from calciol
GO:0047749 IEA cholestanetriol 26-monooxygenase activity
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000033802 cyp27a7 cytochrome P450, family 27, subfamily A, polypeptide 7 protein_coding Danio_rerio
ENSDARG00000055159 cyp27a1.4 cytochrome P450, family 27, subfamily A, polypeptide 1, gene 4 protein_coding Danio_rerio
ENSDARG00000069186 cyp27a1.2 cytochrome P450, family 27, subfamily A, polypeptide 1, gene 2 protein_coding Danio_rerio
ENSDARG00000088013 CYP27A1 (4 of 4) cytochrome P450, family 27, subfamily A, polypeptide 1 protein_coding Danio_rerio
ENSG00000135929 CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1 protein_coding Homo_sapiens

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