C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: TRAF family member-associated NFKB activator
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000136560 TANK 9606 + 2:161136908-161236221 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000259075 TANK-001 161136908-161236187 protein_coding
  ENST00000392749 TANK-002 161160297-161236172 protein_coding
  ENST00000402568 TANK-014 161160349-161235381 protein_coding
  ENST00000403609 TANK-003 161179621-161204979 protein_coding
  ENST00000405852 TANK-004 161160437-161236221 protein_coding
  ENST00000406287 TANK-008 161160349-161235381 protein_coding
  ENST00000429217 TANK-016 161160344-161231017 protein_coding
  ENST00000432002 TANK-015 161136927-161224637 protein_coding
  ENST00000432692 TANK-021 161160428-161224640 nonsense_mediated_decay
  ENST00000437623 TANK-023 161223915-161236166 protein_coding
  ENST00000439442 TANK-020 161231186-161235648 protein_coding
  ENST00000440506 TANK-006 161160299-161204781 protein_coding
  ENST00000441987 TANK-017 161160428-161204774 nonsense_mediated_decay
  ENST00000456358 TANK-012 161160726-161224644 protein_coding
  ENST00000457887 TANK-022 161160406-161224746 nonsense_mediated_decay
  ENST00000461338 TANK-007 161160344-161163518 processed_transcript
  ENST00000463502 TANK-005 161136966-161180085 processed_transcript
  ENST00000468831 TANK-013 161179483-161231175 retained_intron
  ENST00000470324 TANK-019 161223400-161224705 processed_transcript
  ENST00000477952 TANK-009 161160427-161161651 retained_intron
  ENST00000483622 TANK-011 161160457-161161666 retained_intron
  ENST00000489393 TANK-018 161179653-161197528 processed_transcript
  ENST00000494976 TANK-010 161160432-161162890 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000259075ENST00000392749ENST00000405852ENST00000406287ENST00000429217ENST00000439442ENST00000440506ENST00000461338ENST00000463502
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000259075 N/A 2.533±0.00 N/A N/A 3.847±0.00 N/A N/A N/A N/A 2.879±0.00 N/A 1.905±0.20 1.008±0.00 N/A
ENST00000392749 12.796±0.00 7.773±0.00 N/A 4.214±1.61 5.114±0.47 4.246±1.80 3.411±1.80 6.105±2.81 5.675±1.71 9.376±6.33 3.143±2.65 4.815±1.18 2.916±0.72 4.531±1.45
ENST00000405852 N/A 4.766±0.00 1.186±0.00 N/A N/A 2.232±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000406287 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.992±0.00 4.106±0.00
ENST00000429217 N/A N/A 2.911±0.00 3.142±0.00 N/A N/A N/A 6.210±0.00 4.010±0.00 N/A N/A N/A N/A N/A
ENST00000439442 N/A N/A N/A N/A N/A N/A 5.216±0.00 N/A N/A 15.179±0.00 8.964±0.00 12.670±2.26 5.484±2.19 10.715±0.00
ENST00000440506 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 14.196±0.00 8.343±0.00 13.871±0.00
ENST00000461338 N/A N/A 2.155±0.00 N/A N/A N/A N/A N/A N/A N/A 2.913±0.00 6.533±0.00 N/A N/A
ENST00000463502 N/A N/A N/A N/A N/A N/A N/A N/A 9.853±0.00 N/A N/A 10.442±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005KZ CIL_0005KZ_0001 CGP 2:160272151-161236221
CIL_0008JH CIL_0008JH_0001 VISTA 2:160938384-161538940
CIL_0005L0 CIL_0005L0_0001 CGP 2:161136908-161411717

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0007165 TAS signal transduction
GO:0007249 IEA I-kappaB kinase/NF-kappaB signaling
GO:0031625 IPI ubiquitin protein ligase binding
GO:0045087 TAS innate immune response
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000067723 tank TRAF family member-associated NFKB activator protein_coding Danio_rerio
ENSDARG00000090402 tank TRAF family member-associated NFKB activator protein_coding Danio_rerio
ENSMUSG00000064289 Tank TRAF family member-associated Nf-kappa B activator protein_coding Mus_musculus

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