C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: leucine rich repeat containing 8 family, member A
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000136802 LRRC8A 9606 + 9:128882112-128918039 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000259324 LRRC8A-201 128882502-128918034 protein_coding
  ENST00000372599 LRRC8A-002 128882196-128918036 protein_coding
  ENST00000372600 LRRC8A-001 128882112-128918039 protein_coding
  ENST00000483638 LRRC8A-004 128884995-128886090 processed_transcript
  ENST00000492784 LRRC8A-003 128912744-128916739 processed_transcript

Homo sapiens EnsemblGRCh38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000259324ENST00000372599ENST00000372600
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000259324 N/A N/A N/A N/A N/A N/A N/A N/A 1.210±0.00 N/A 0.224±0.00 N/A N/A N/A
ENST00000372599 4.453±0.00 9.446±0.00 1.510±0.00 6.802±3.17 4.527±2.33 3.922±2.05 1.094±0.51 5.371±0.02 1.372±0.00 10.043±5.82 1.358±0.10 7.687±3.16 13.817±7.98 7.264±0.98
ENST00000372600 24.445±0.00 7.320±0.00 1.019±0.00 13.517±11.30 3.477±1.77 5.930±5.38 6.816±6.51 12.502±0.00 1.246±0.66 20.001±0.00 3.297±0.00 9.713±7.03 11.293±3.91 5.993±2.65

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005L9 CIL_0005L9_0001 CGP 9:128819651-128882494
CIL_0003BM CIL_0003BM_0001 CGP 9:128882112-128942041

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002329 ISS pre-B cell differentiation
GO:0005253 IMP anion channel activity
GO:0005515 IPI:IEA protein binding
GO:0005886 IDA plasma membrane
GO:0006820 IMP anion transport
GO:0006884 IMP cell volume homeostasis
GO:0006970 IMP response to osmotic stress
GO:0009986 IDA cell surface
GO:0016020 IDA membrane
GO:0034702 IDA ion channel complex

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000032188 lrrc8a leucine rich repeat containing 8 family, member A protein_coding Danio_rerio
ENSDARG00000052155 LRRC8A (2 of 2) leucine rich repeat containing 8 family, member A protein_coding Danio_rerio
ENSMUSG00000099041 Gm28035 predicted gene, 28035 protein_coding Mus_musculus

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