C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: leucine rich repeat containing 8 family, member A
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000372600 LRRC8A-001 ENSG00000136802 9606 + 9:128882112-128918039 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000372600
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000372600 24.445±0.00 7.320±0.00 1.019±0.00 13.517±11.30 3.477±1.77 5.930±5.38 6.816±6.51 12.502±0.00 1.246±0.66 20.001±0.00 3.297±0.00 9.713±7.03 11.293±3.91 5.993±2.65

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005L9 CIL_0005L9_0001 CGP 9:128819651-128882494
CIL_0003BM CIL_0003BM_0001 CGP 9:128882112-128942041

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002329 ISS pre-B cell differentiation
GO:0005253 IMP anion channel activity
GO:0005515 IPI:IEA protein binding
GO:0005886 IDA plasma membrane
GO:0006820 IMP anion transport
GO:0006884 IMP cell volume homeostasis
GO:0006970 IMP response to osmotic stress
GO:0009986 IDA cell surface
GO:0016020 IDA membrane
GO:0034702 IDA ion channel complex

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000095078 Lrrc8a-001 protein_coding Mus_musculus 0 3696
ENSMUST00000139454 Gm28035-001 nonsense_mediated_decay Mus_musculus 0 3646
ENSMUST00000113654 Lrrc8a-002 protein_coding Mus_musculus 0 3565
ENSDART00000148138 lrrc8a-001 protein_coding Danio_rerio 0 1648
ENSDART00000073953 LRRC8A (2 of 2)-201 protein_coding Danio_rerio 0 1314
ENSDART00000144732 LRRC8A (2 of 2)-001 protein_coding Danio_rerio 0 1314

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