C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: leucine rich repeat containing 8 family, member A
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000372599 LRRC8A-002 ENSG00000136802 9606 + 9:128882196-128918036 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000372599
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000372599 4.453±0.00 9.446±0.00 1.510±0.00 6.802±3.17 4.527±2.33 3.922±2.05 1.094±0.51 5.371±0.02 1.372±0.00 10.043±5.82 1.358±0.10 7.687±3.16 13.817±7.98 7.264±0.98

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005L9 CIL_0005L9_0001 CGP 9:128819651-128882494
CIL_0003BM CIL_0003BM_0001 CGP 9:128882112-128942041

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002329 ISS pre-B cell differentiation
GO:0005253 IMP anion channel activity
GO:0005515 IPI:IEA protein binding
GO:0005886 IDA plasma membrane
GO:0006820 IMP anion transport
GO:0006884 IMP cell volume homeostasis
GO:0006970 IMP response to osmotic stress
GO:0009986 IDA cell surface
GO:0016020 IDA membrane
GO:0034702 IDA ion channel complex

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000113654 Lrrc8a-002 protein_coding Mus_musculus 0 3603
ENSMUST00000095078 Lrrc8a-001 protein_coding Mus_musculus 0 3565
ENSMUST00000139454 Gm28035-001 nonsense_mediated_decay Mus_musculus 0 3565
ENSDART00000148138 lrrc8a-001 protein_coding Danio_rerio 0 1648
ENSDART00000073953 LRRC8A (2 of 2)-201 protein_coding Danio_rerio 0 1314
ENSDART00000144732 LRRC8A (2 of 2)-001 protein_coding Danio_rerio 0 1314

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