C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: DENN/MADD domain containing 4C
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000137145 DENND4C 9606 + 9:19230435-19373545 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000361024 DENND4C-003 19346556-19373545 protein_coding
  ENST00000380424 DENND4C-004 19346728-19357695 protein_coding
  ENST00000380427 DENND4C-002 19342669-19372880 protein_coding
  ENST00000380437 DENND4C-008 19290758-19372594 retained_intron
  ENST00000434457 DENND4C-006 19230435-19372598 protein_coding
  ENST00000494124 DENND4C-009 19290758-19372594 nonsense_mediated_decay
  ENST00000602442 DENND4C-010 19336404-19341044 retained_intron
  ENST00000602708 DENND4C-007 19230797-19276671 retained_intron
  ENST00000602925 DENND4C-005 19230435-19372858 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000361024ENST00000380427ENST00000380437ENST00000434457ENST00000494124ENST00000602925
Transcript ID Adipose Adrenal Bladder Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000361024 N/A 3.174±0.00 N/A 1.415±0.00 2.462±0.00 1.809±0.00 1.289±0.00 N/A 2.817±0.00 0.886±0.00 5.663±0.66 2.391±1.52 3.393±0.81
ENST00000380427 2.431±0.00 N/A N/A 2.531±0.00 N/A N/A 1.789±0.00 1.105±0.00 N/A N/A 2.095±0.00 1.552±0.00 N/A
ENST00000380437 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.115±0.00
ENST00000434457 N/A 1.761±0.00 2.028±0.00 7.285±0.00 7.302±0.00 0.422±0.00 0.822±0.00 3.016±0.00 N/A N/A 2.736±2.16 3.135±0.00 1.236±0.00
ENST00000494124 N/A N/A N/A N/A N/A N/A 1.619±0.00 N/A N/A N/A 2.835±0.00 N/A N/A
ENST00000602925 N/A N/A N/A N/A N/A 0.887±0.00 N/A 4.099±0.00 N/A 1.183±0.00 1.463±0.51 2.209±0.00 1.501±0.43

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007DE CIL_0007DE_0001 CGP 9:19108375-19373545
CIL_0007DD CIL_0007DD_0001 CGP 9:19230435-19380254

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005829 ISS cytosol
GO:0005886 ISS plasma membrane
GO:0015031 IEA protein transport
GO:0017112 IDA Rab guanyl-nucleotide exchange factor activity
GO:0030904 IEA retromer complex
GO:0032593 ISS insulin-responsive compartment
GO:0032851 IDA positive regulation of Rab GTPase activity
GO:0032869 ISS cellular response to insulin stimulus
GO:0072659 ISS protein localization to plasma membrane

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000059571 dennd4c DENN/MADD domain containing 4C protein_coding Danio_rerio
ENSMUSG00000038024 Dennd4c DENN/MADD domain containing 4C protein_coding Mus_musculus

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