C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: DENN/MADD domain containing 4C
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000038024 Dennd4c 10090 + 4:86748555-86850603 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000045512 Dennd4c-201 86748555-86830167 protein_coding
  ENSMUST00000082026 Dennd4c-001 86748555-86850603 protein_coding
  ENSMUST00000128710 Dennd4c-002 86777843-86781752 processed_transcript
  ENSMUST00000142837 Dennd4c-003 86774255-86849055 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000045512ENSMUST00000082026ENSMUST00000142837
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000045512 N/A 1.572±0.26 N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.740±0.65 N/A N/A
ENSMUST00000082026 7.213±3.59 3.991±0.69 6.925±0.07 2.272±0.83 5.021±0.52 8.432±0.29 2.562±0.75 3.217±0.31 2.494±0.52 6.206±0.76 1.800±0.57 6.106±2.29 5.161±3.33 2.999±0.46
ENSMUST00000142837 1.004±0.10 N/A N/A 1.289±0.00 0.986±0.00 N/A 0.764±0.11 0.549±0.01 0.600±0.13 N/A N/A 5.683±0.00 1.608±0.73 2.897±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007DE CIL_0007DE_0002 CGP 4:86648386-86850603
CIL_0007DD CIL_0007DD_0002 CGP 4:86748555-86857412

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005829 IDA cytosol
GO:0005886 IDA plasma membrane
GO:0015031 IEA protein transport
GO:0017112 IDA Rab guanyl-nucleotide exchange factor activity
GO:0030904 IDA retromer complex
GO:0032593 IDA insulin-responsive compartment
GO:0032851 IDA positive regulation of Rab GTPase activity
GO:0032869 IMP cellular response to insulin stimulus
GO:0072659 IMP protein localization to plasma membrane

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000059571 dennd4c DENN/MADD domain containing 4C protein_coding Danio_rerio
ENSG00000137145 DENND4C DENN/MADD domain containing 4C protein_coding Homo_sapiens

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