C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: flotillin 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000137312 FLOT1 9606 - 6:30727709-30742733 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000376389 FLOT1-001 30727709-30742733 protein_coding
  ENST00000413165 FLOT1-008 30730919-30742307 protein_coding
  ENST00000416018 FLOT1-010 30740255-30742203 protein_coding
  ENST00000418160 FLOT1-007 30740161-30742357 protein_coding
  ENST00000438162 FLOT1-006 30731067-30742500 protein_coding
  ENST00000445853 FLOT1-009 30740176-30742276 protein_coding
  ENST00000454845 FLOT1-005 30740509-30742524 protein_coding
  ENST00000470643 FLOT1-002 30740158-30742732 processed_transcript
  ENST00000476729 FLOT1-012 30730991-30740794 retained_intron
  ENST00000484168 FLOT1-003 30740254-30742706 retained_intron
  ENST00000484693 FLOT1-004 30741354-30742677 retained_intron
  ENST00000487376 FLOT1-011 30727709-30740853 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000376389ENST00000413165ENST00000416018ENST00000445853ENST00000470643ENST00000476729ENST00000487376
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000376389 17.907±0.00 27.946±0.00 1.704±0.00 11.137±5.13 10.010±4.62 16.317±0.00 11.554±9.58 10.358±7.02 6.704±4.02 18.448±12.76 7.180±2.02 26.193±21.52 48.941±9.60 18.812±0.00
ENST00000413165 N/A N/A 3.718±0.00 17.413±0.00 7.475±0.00 2.846±0.00 4.299±0.00 7.180±0.00 10.036±0.00 N/A 7.921±0.00 12.830±0.00 N/A N/A
ENST00000416018 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 41.635±0.00 N/A 39.446±0.00
ENST00000445853 N/A N/A 5.166±0.00 10.019±0.00 6.174±0.00 3.974±0.00 5.739±0.00 N/A 5.121±0.00 10.592±0.00 N/A 28.726±0.00 N/A 25.228±0.00
ENST00000470643 N/A N/A N/A N/A N/A N/A N/A 3.257±0.00 N/A N/A N/A 63.504±0.00 113.662±0.00 65.566±0.00
ENST00000476729 N/A N/A N/A N/A N/A 5.278±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000487376 N/A N/A 1.348±0.00 N/A N/A N/A N/A 1.659±0.00 N/A N/A N/A 16.204±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00090O CIL_00090O_0001 VISTA 6:30539989-31144784

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002020 IPI protease binding
GO:0005515 IPI protein binding
GO:0005765 IDA lysosomal membrane
GO:0005768 IDA endosome
GO:0005815 IDA microtubule organizing center
GO:0005886 IEA plasma membrane
GO:0005901 TAS caveola
GO:0005925 IDA focal adhesion
GO:0007409 IEA axonogenesis
GO:0008180 IDA COP9 signalosome
GO:0016020 IDA membrane
GO:0016021 TAS integral component of membrane
GO:0016600 IEA flotillin complex
GO:0022617 IMP extracellular matrix disassembly
GO:0034451 IDA centriolar satellite
GO:0035023 IEA regulation of Rho protein signal transduction
GO:0035255 IEA ionotropic glutamate receptor binding
GO:0042383 IEA sarcolemma
GO:0045121 IDA membrane raft
GO:0070062 IDA extracellular vesicular exosome
GO:0072659 IEA protein localization to plasma membrane
GO:0090002 IMP establishment of protein localization to plasma membrane

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000001710 flot1a flotillin 1a protein_coding Danio_rerio
ENSDARG00000037998 flot1b flotillin 1b protein_coding Danio_rerio
ENSMUSG00000059714 Flot1 flotillin 1 protein_coding Mus_musculus

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