C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: flotillin 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000059714 Flot1 10090 + 17:35823230-35832791 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000001569 Flot1-001 35823230-35832791 protein_coding
  ENSMUST00000172846 Flot1-003 35823593-35825744 protein_coding
  ENSMUST00000173147 Flot1-006 35823549-35825757 protein_coding
  ENSMUST00000173273 Flot1-009 35830499-35832640 retained_intron
  ENSMUST00000173337 Flot1-004 35823996-35824928 retained_intron
  ENSMUST00000173381 Flot1-008 35830086-35832626 retained_intron
  ENSMUST00000173493 Flot1-005 35823526-35825745 protein_coding
  ENSMUST00000173628 Flot1-002 35823382-35830024 nonsense_mediated_decay
  ENSMUST00000174080 Flot1-011 35823347-35832610 protein_coding
  ENSMUST00000174227 Flot1-007 35823426-35824398 retained_intron
  ENSMUST00000174297 Flot1-010 35830638-35831470 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000001569ENSMUST00000173147ENSMUST00000173628ENSMUST00000174080
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000001569 40.331±12.05 34.917±2.96 55.101±8.02 22.433±4.11 27.635±11.28 28.130±2.22 61.646±5.57 20.790±1.16 15.544±4.97 41.748±3.18 24.488±4.80 27.724±4.38 18.516±0.95 4.779±1.38
ENSMUST00000173147 N/A N/A N/A N/A 9.809±0.00 N/A N/A N/A N/A N/A N/A 15.874±0.88 N/A N/A
ENSMUST00000173628 N/A N/A 21.098±4.70 117.909±0.00 N/A N/A N/A N/A 6.557±0.00 N/A N/A 27.183±31.34 40.872±36.88 3.214±0.00
ENSMUST00000174080 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 10.471±1.21 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00090O CIL_00090O_0002 VISTA 17:35419853-36021785
CIL_0001X1 CIL_0001X1_0002 CGP 17:35823230-35838306

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002020 IEA protease binding
GO:0005515 IPI protein binding
GO:0005765 IEA lysosomal membrane
GO:0005768 ISS endosome
GO:0005815 IEA microtubule organizing center
GO:0005886 IDA plasma membrane
GO:0005901 IDA caveola
GO:0005925 IEA focal adhesion
GO:0007409 IMP axonogenesis
GO:0008180 IEA COP9 signalosome
GO:0016020 IDA membrane
GO:0016600 IDA flotillin complex
GO:0022617 IEA extracellular matrix disassembly
GO:0034451 IEA centriolar satellite
GO:0035023 IMP regulation of Rho protein signal transduction
GO:0035255 IEA ionotropic glutamate receptor binding
GO:0042383 IDA sarcolemma
GO:0045121 IDA membrane raft
GO:0070062 IEA extracellular vesicular exosome
GO:0072659 IMP protein localization to plasma membrane
GO:0090002 IEA establishment of protein localization to plasma membrane

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000001710 flot1a flotillin 1a protein_coding Danio_rerio
ENSDARG00000037998 flot1b flotillin 1b protein_coding Danio_rerio
ENSG00000137312 FLOT1 flotillin 1 protein_coding Homo_sapiens

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