C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: transmembrane protease, serine 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000137648 TMPRSS4 9606 + 11:118077012-118121890 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000437212 TMPRSS4-004 118077089-118118459 protein_coding
  ENST00000517483 TMPRSS4-007 118077078-118118444 nonsense_mediated_decay
  ENST00000517544 TMPRSS4-015 118099043-118108223 protein_coding
  ENST00000518413 TMPRSS4-022 118111871-118118155 processed_transcript
  ENST00000518610 TMPRSS4-016 118113276-118115047 retained_intron
  ENST00000519126 TMPRSS4-003 118077038-118095400 retained_intron
  ENST00000519236 TMPRSS4-002 118077071-118118450 nonsense_mediated_decay
  ENST00000519813 TMPRSS4-012 118102940-118108867 retained_intron
  ENST00000520063 TMPRSS4-013 118077173-118099171 retained_intron
  ENST00000522151 TMPRSS4-011 118077130-118111835 protein_coding
  ENST00000522307 TMPRSS4-005 118077076-118118091 protein_coding
  ENST00000522462 TMPRSS4-020 118094821-118107876 retained_intron
  ENST00000522824 TMPRSS4-008 118077094-118118457 protein_coding
  ENST00000523251 TMPRSS4-006 118077077-118118182 protein_coding
  ENST00000523770 TMPRSS4-014 118114871-118115560 retained_intron
  ENST00000524218 TMPRSS4-017 118113292-118118450 protein_coding
  ENST00000528118 TMPRSS4-021 118105567-118115219 retained_intron
  ENST00000534111 TMPRSS4-001 118077038-118121890 protein_coding
  ENST00000610964 TMPRSS4-201 118077096-118118450 protein_coding
  ENST00000616579 TMPRSS4-202 118077012-118119839 protein_coding
  ENST00000618855 TMPRSS4-203 118077012-118119839 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000437212ENST00000517544ENST00000518413ENST00000518610ENST00000519236ENST00000522151ENST00000522307ENST00000523251ENST00000524218ENST00000528118ENST00000534111ENST00000610964ENST00000616579ENST00000618855
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000437212 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 15.001±0.00 N/A N/A
ENST00000517544 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.050±0.00 N/A
ENST00000518413 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.240±0.00 N/A
ENST00000518610 N/A N/A N/A N/A N/A N/A 1.739±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000519236 N/A N/A N/A N/A 2.726±0.00 5.384±0.00 N/A N/A N/A 2.126±0.00 N/A 15.475±14.87 0.183±0.00 N/A
ENST00000522151 0.225±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000522307 N/A N/A N/A N/A N/A N/A N/A 1.701±0.00 N/A 1.527±1.17 N/A 3.815±0.00 N/A N/A
ENST00000523251 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.772±0.00 N/A N/A N/A
ENST00000524218 0.202±0.00 N/A N/A N/A N/A 11.139±0.00 N/A N/A N/A 4.303±0.00 0.276±0.00 N/A 0.138±0.03 N/A
ENST00000528118 0.041±0.00 0.213±0.00 0.233±0.00 0.009±0.00 0.108±0.00 N/A N/A N/A 0.246±0.00 0.643±0.00 N/A 0.481±0.46 0.011±0.00 0.189±0.05
ENST00000534111 0.039±0.00 0.056±0.00 N/A N/A 0.038±0.00 1.548±0.00 N/A 0.062±0.00 N/A N/A 0.017±0.00 N/A 0.009±0.00 N/A
ENST00000610964 N/A N/A N/A N/A N/A 3.524±0.00 N/A 4.028±0.00 N/A N/A N/A 20.277±20.09 N/A 1.298±0.00
ENST00000616579 N/A N/A 0.157±0.00 N/A N/A 1.522±0.00 N/A N/A 0.508±0.00 N/A N/A N/A N/A N/A
ENST00000618855 N/A N/A N/A N/A 1.089±0.00 3.605±0.00 N/A 0.779±0.00 N/A 0.865±0.00 N/A 1.589±0.47 0.036±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002BW CIL_0002BW_0002 CGP 11:118077012-118152888

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003824 IEA catalytic activity
GO:0004252 NAS:IEA serine-type endopeptidase activity
GO:0005044 IEA scavenger receptor activity
GO:0005515 IEA protein binding
GO:0006508 NAS:IEA proteolysis
GO:0006898 IEA receptor-mediated endocytosis
GO:0008152 IEA metabolic process
GO:0016020 IEA membrane
GO:0016021 NAS integral component of membrane

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000006693 tmprss4a transmembrane protease, serine 4a protein_coding Danio_rerio
ENSDARG00000012860 tmprss4b transmembrane protease, serine 4b protein_coding Danio_rerio
ENSMUSG00000032091 Tmprss4 transmembrane protease, serine 4 protein_coding Mus_musculus

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