C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cancer susceptibility candidate 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000137812 CASC5 9606 + 15:40594020-40664342 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000346991 CASC5-002 40594020-40664342 protein_coding
  ENST00000399668 CASC5-001 40594249-40662683 protein_coding
  ENST00000526913 CASC5-013 40623132-40664339 nonsense_mediated_decay
  ENST00000527044 CASC5-201 40594249-40625584 protein_coding
  ENST00000528967 CASC5-009 40646886-40650365 retained_intron
  ENST00000528975 CASC5-005 40594034-40610289 protein_coding
  ENST00000531626 CASC5-012 40662573-40663904 processed_transcript
  ENST00000532056 CASC5-006 40594249-40610297 protein_coding
  ENST00000532347 CASC5-010 40650127-40654977 retained_intron
  ENST00000532406 CASC5-008 40628074-40647038 protein_coding
  ENST00000533001 CASC5-004 40594265-40626042 retained_intron
  ENST00000534204 CASC5-007 40594272-40645712 nonsense_mediated_decay
  ENST00000614337 CASC5-003 40594035-40623159 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000346991ENST00000399668ENST00000526913ENST00000527044ENST00000528967ENST00000531626ENST00000533001ENST00000614337
Transcript ID Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000346991 N/A 0.028±0.01 N/A N/A N/A N/A N/A N/A N/A 0.293±0.28 0.147±0.00 4.503±3.06
ENST00000399668 N/A N/A 0.171±0.00 1.202±0.00 N/A 0.068±0.00 N/A N/A N/A 0.890±0.57 0.177±0.00 N/A
ENST00000526913 0.160±0.00 N/A 0.649±0.00 N/A N/A 0.110±0.03 0.028±0.00 0.019±0.00 0.010±0.00 0.845±0.81 0.585±0.00 9.454±4.93
ENST00000527044 N/A N/A 0.639±0.00 N/A N/A N/A N/A 0.208±0.00 N/A N/A 0.066±0.00 N/A
ENST00000528967 N/A N/A N/A N/A N/A N/A N/A 0.416±0.00 N/A N/A N/A N/A
ENST00000531626 N/A N/A N/A N/A N/A N/A 0.093±0.00 N/A N/A N/A N/A N/A
ENST00000533001 0.120±0.00 N/A N/A N/A 0.017±0.00 N/A N/A 0.185±0.00 N/A N/A N/A N/A
ENST00000614337 N/A N/A N/A N/A 0.018±0.00 N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00070F CIL_00070F_0001 CGP 15:40569300-40664342

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000278 TAS mitotic cell cycle
GO:0000776 IEA kinetochore
GO:0001669 IDA acrosomal vesicle
GO:0001675 NAS acrosome assembly
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0006334 TAS nucleosome assembly
GO:0007067 IEA mitotic nuclear division
GO:0008608 IDA attachment of spindle microtubules to kinetochore
GO:0010923 IDA negative regulation of phosphatase activity
GO:0034080 TAS CENP-A containing nucleosome assembly
GO:0034501 IDA protein localization to kinetochore
GO:0070062 IDA extracellular vesicular exosome
GO:0071173 IDA spindle assembly checkpoint

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000070239 casc5 cancer susceptibility candidate 5 protein_coding Danio_rerio
ENSMUSG00000027326 Casc5 cancer susceptibility candidate 5 protein_coding Mus_musculus

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