C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cytochrome P450, family 2, subfamily C, polypeptide 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000138115 CYP2C8 9606 - 10:95036772-95069497 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000371270 CYP2C8-001 95036773-95069497 protein_coding
  ENST00000479946 CYP2C8-002 95038959-95069497 retained_intron
  ENST00000490994 CYP2C8-008 95036773-95069497 nonsense_mediated_decay
  ENST00000525991 CYP2C8-007 95036984-95069497 nonsense_mediated_decay
  ENST00000526814 CYP2C8-005 95036778-95069486 retained_intron
  ENST00000527420 CYP2C8-003 95036773-95069403 nonsense_mediated_decay
  ENST00000527953 CYP2C8-006 95036778-95069486 retained_intron
  ENST00000531714 CYP2C8-011 95037182-95039375 retained_intron
  ENST00000533320 CYP2C8-004 95036802-95069427 retained_intron
  ENST00000535898 CYP2C8-201 95036772-95069497 protein_coding
  ENST00000539050 CYP2C8-202 95036772-95069497 protein_coding
  ENST00000623108 CYP2C8-203 95036772-95069497 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000371270ENST00000479946ENST00000490994ENST00000525991ENST00000527420ENST00000531714ENST00000533320ENST00000535898ENST00000539050ENST00000623108
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000371270 N/A N/A N/A N/A N/A N/A N/A 187.477±0.00 N/A N/A N/A N/A N/A
ENST00000479946 0.024±0.00 N/A N/A 0.124±0.00 N/A 0.030±0.00 N/A N/A N/A N/A 0.059±0.00 N/A N/A
ENST00000490994 N/A N/A N/A N/A 0.077±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000525991 N/A N/A N/A 0.279±0.00 N/A N/A N/A 0.102±0.00 N/A N/A N/A 0.051±0.00 N/A
ENST00000527420 N/A N/A 0.403±0.00 N/A 0.084±0.00 N/A N/A 46.154±0.00 77.803±0.00 N/A 0.413±0.00 N/A 0.089±0.00
ENST00000531714 N/A 0.101±0.00 0.324±0.00 N/A N/A N/A N/A N/A 0.131±0.00 N/A N/A 0.037±0.00 0.202±0.00
ENST00000533320 N/A 0.270±0.00 N/A 0.151±0.00 N/A N/A 0.050±0.00 16.902±16.47 N/A N/A 0.215±0.00 N/A 0.105±0.00
ENST00000535898 N/A N/A N/A N/A N/A N/A 0.060±0.00 N/A 127.205±0.00 N/A 0.268±0.00 0.074±0.00 N/A
ENST00000539050 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.117±0.00 N/A N/A N/A
ENST00000623108 N/A N/A N/A N/A 0.078±0.00 N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007H6 CIL_0007H6_0003 CGP 10:94938658-95069497

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004497 IDA monooxygenase activity
GO:0005506 IEA iron ion binding
GO:0005789 TAS endoplasmic reticulum membrane
GO:0006082 IDA organic acid metabolic process
GO:0006805 TAS xenobiotic metabolic process
GO:0016705 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0017144 IDA drug metabolic process
GO:0019369 TAS arachidonic acid metabolic process
GO:0019373 TAS epoxygenase P450 pathway
GO:0020037 IEA heme binding
GO:0034875 IDA caffeine oxidase activity
GO:0042738 IDA exogenous drug catabolic process
GO:0044281 TAS small molecule metabolic process
GO:0055114 IDA:IEA oxidation-reduction process
GO:0070330 IEA aromatase activity
GO:0070989 IDA oxidative demethylation
GO:0097267 TAS omega-hydroxylase P450 pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000007173 cyp2y3 cytochrome P450, family 2, subfamily Y, polypeptide 3 protein_coding Danio_rerio
ENSDARG00000068493 si:zfos-411a11.2 si:zfos-411a11.2 protein_coding Danio_rerio
ENSMUSG00000003053 Cyp2c29 cytochrome P450, family 2, subfamily c, polypeptide 29 protein_coding Mus_musculus
ENSMUSG00000025003 Cyp2c39 cytochrome P450, family 2, subfamily c, polypeptide 39 protein_coding Mus_musculus
ENSMUSG00000025004 Cyp2c40 cytochrome P450, family 2, subfamily c, polypeptide 40 protein_coding Mus_musculus
ENSMUSG00000032808 Cyp2c38 cytochrome P450, family 2, subfamily c, polypeptide 38 protein_coding Mus_musculus
ENSMUSG00000042248 Cyp2c37 cytochrome P450, family 2. subfamily c, polypeptide 37 protein_coding Mus_musculus
ENSMUSG00000054827 Cyp2c50 cytochrome P450, family 2, subfamily c, polypeptide 50 protein_coding Mus_musculus
ENSMUSG00000062624 Cyp2c67 cytochrome P450, family 2, subfamily c, polypeptide 67 protein_coding Mus_musculus
ENSMUSG00000067225 Cyp2c54 cytochrome P450, family 2, subfamily c, polypeptide 54 protein_coding Mus_musculus
ENSMUSG00000067229 Cyp2c66 cytochrome P450, family 2, subfamily c, polypeptide 66 protein_coding Mus_musculus
ENSMUSG00000067231 Cyp2c65 cytochrome P450, family 2, subfamily c, polypeptide 65 protein_coding Mus_musculus
ENSMUSG00000074882 Cyp2c68 cytochrome P450, family 2, subfamily c, polypeptide 68 protein_coding Mus_musculus
ENSMUSG00000092008 Cyp2c69 cytochrome P450, family 2, subfamily c, polypeptide 69 protein_coding Mus_musculus

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