C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: myostatin
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000138379 MSTN 9606 - 2:190055697-190062729 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000260950 MSTN-001 190055697-190062729 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000260950
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000260950 0.037±0.00 0.220±0.00 0.201±0.00 0.106±0.06 0.384±0.00 0.036±0.01 0.015±0.01 0.112±0.00 0.015±0.00 0.025±0.00 0.153±0.05 0.072±0.05 0.019±0.01 0.095±0.02

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002KB CIL_0002KB_0001 CGP 2:189879609-190203484

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005102 IPI receptor binding
GO:0005125 IEA cytokine activity
GO:0005515 IPI protein binding
GO:0005615 IEA extracellular space
GO:0005737 IEA cytoplasm
GO:0007179 IEA transforming growth factor beta receptor signaling pathway
GO:0007517 TAS muscle organ development
GO:0008083 IEA growth factor activity
GO:0008201 IEA heparin binding
GO:0009408 IEA response to heat
GO:0009629 IEA response to gravity
GO:0014732 IEA skeletal muscle atrophy
GO:0014741 IEA negative regulation of muscle hypertrophy
GO:0014850 IEA response to muscle activity
GO:0022602 IEA ovulation cycle process
GO:0033574 IEA response to testosterone
GO:0040007 IEA growth
GO:0042802 IPI identical protein binding
GO:0043403 IEA skeletal muscle tissue regeneration
GO:0043627 IEA response to estrogen
GO:0045471 IEA response to ethanol
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0048632 IEA negative regulation of skeletal muscle tissue growth
GO:0051384 IEA response to glucocorticoid
GO:0051602 IEA response to electrical stimulus
GO:0071549 IEA cellular response to dexamethasone stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000042947 mstna myostatin a protein_coding Danio_rerio
ENSDARG00000069133 mstnb myostatin b protein_coding Danio_rerio
ENSMUSG00000026100 Mstn myostatin protein_coding Mus_musculus

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