C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: myostatin
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000026100 Mstn 10090 + 1:53061640-53068079 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000027269 Mstn-001 53061640-53068079 protein_coding
  ENSMUST00000191197 Mstn-002 53061657-53068045 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000027269ENSMUST00000191197
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000027269 0.127±0.03 0.112±0.00 0.081±0.01 14.556±1.72 0.045±0.00 0.313±0.17 0.138±0.02 0.031±0.04 0.233±0.07 20.889±4.43 0.006±0.00 0.044±0.02 0.044±0.02
ENSMUST00000191197 0.067±0.00 N/A 0.098±0.00 N/A N/A N/A 0.022±0.00 0.009±0.00 N/A N/A N/A N/A 0.029±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002KB CIL_0002KB_0002 CGP 1:52922324-53068079

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005102 IPI receptor binding
GO:0005125 IEA cytokine activity
GO:0005515 IPI protein binding
GO:0005615 IEA extracellular space
GO:0005737 IEA cytoplasm
GO:0007179 IDA transforming growth factor beta receptor signaling pathway
GO:0008083 IEA growth factor activity
GO:0008201 IEA heparin binding
GO:0009408 IEA response to heat
GO:0009629 IEA response to gravity
GO:0014732 IEA skeletal muscle atrophy
GO:0014741 IEA negative regulation of muscle hypertrophy
GO:0014850 IEA response to muscle activity
GO:0022602 IEA ovulation cycle process
GO:0033574 IEA response to testosterone
GO:0042802 IEA identical protein binding
GO:0043403 IEA skeletal muscle tissue regeneration
GO:0043627 IEA response to estrogen
GO:0045471 IEA response to ethanol
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0048632 IEA negative regulation of skeletal muscle tissue growth
GO:0051384 IEA response to glucocorticoid
GO:0051602 IEA response to electrical stimulus
GO:0071549 IDA cellular response to dexamethasone stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000042947 mstna myostatin a protein_coding Danio_rerio
ENSDARG00000069133 mstnb myostatin b protein_coding Danio_rerio
ENSG00000138379 MSTN myostatin protein_coding Homo_sapiens

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