C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: HECT and RLD domain containing E3 ubiquitin protein ligase 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000138641 HERC3 9606 + 4:88521048-88708542 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000264345 HERC3-201 88605794-88708541 protein_coding
  ENST00000402738 HERC3-001 88592423-88708542 protein_coding
  ENST00000407637 HERC3-002 88592496-88657434 protein_coding
  ENST00000422770 HERC3-004 88592484-88649895 protein_coding
  ENST00000426683 HERC3-005 88593251-88649998 protein_coding
  ENST00000431413 HERC3-003 88592434-88652020 protein_coding
  ENST00000452979 HERC3-006 88593378-88653088 protein_coding
  ENST00000470815 HERC3-007 88658268-88670202 retained_intron
  ENST00000504994 HERC3-008 88667456-88668653 processed_transcript
  ENST00000512194 HERC3-009 88670139-88687299 protein_coding
  ENST00000513325 HERC3-010 88523810-88649847 protein_coding
  ENST00000597259 HERC3-012 88523856-88524991 processed_transcript
  ENST00000598772 HERC3-011 88523826-88524983 processed_transcript
  ENST00000601319 HERC3-013 88521048-88523813 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000264345ENST00000402738ENST00000407637ENST00000601319
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000264345 2.096±0.00 2.887±0.00 N/A 4.256±1.13 2.286±0.80 3.620±0.00 3.994±1.33 3.890±0.39 2.753±1.78 3.686±1.30 2.679±0.21 2.931±0.07 3.415±0.49 2.662±0.00
ENST00000402738 2.601±0.00 2.113±0.00 3.464±0.00 3.514±0.46 1.435±0.00 2.030±0.00 3.279±0.00 2.411±0.00 1.664±0.00 2.580±0.00 0.987±0.00 3.572±0.00 2.492±0.62 N/A
ENST00000407637 N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.084±0.00 N/A N/A N/A N/A
ENST00000601319 25.660±0.00 32.979±0.00 4.878±0.00 18.117±7.95 17.919±11.59 21.327±15.63 11.943±9.34 19.835±10.93 13.527±4.48 19.902±13.81 8.769±3.19 17.486±12.98 32.280±14.82 23.702±10.32

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004842 IBA:IEA ubiquitin-protein transferase activity
GO:0005634 IBA nucleus
GO:0016567 IEA protein ubiquitination
GO:0016874 IEA ligase activity
GO:0031410 IEA cytoplasmic vesicle
GO:0042787 IBA protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000075887 herc3 hect domain and RLD 3 protein_coding Danio_rerio
ENSMUSG00000029804 Herc3 hect domain and RLD 3 protein_coding Mus_musculus

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