C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein kinase, cGMP-dependent, type II
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000138669 PRKG2 9606 - 4:81087370-81215117 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000264399 PRKG2-201 81087370-81215117 protein_coding
  ENST00000395578 PRKG2-001 81088683-81215034 protein_coding
  ENST00000456882 PRKG2-004 81140628-81154144 processed_transcript
  ENST00000509169 PRKG2-002 81089493-81154157 processed_transcript
  ENST00000509474 PRKG2-003 81089597-81154253 processed_transcript
  ENST00000545647 PRKG2-202 81087370-81153732 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastHeartLungMuscleOvaryPlacentaTestisENST00000264399ENST00000395578ENST00000456882ENST00000509474ENST00000545647
Transcript ID Adipose Adrenal Bladder Brain Breast Heart Lung Muscle Ovary Placenta Testis
ENST00000264399 N/A 0.048±0.00 0.035±0.00 N/A 0.145±0.07 0.023±0.00 N/A N/A 0.022±0.01 0.015±0.00 0.273±0.18
ENST00000395578 N/A N/A N/A 0.121±0.00 0.170±0.00 N/A 0.337±0.00 N/A 0.054±0.02 N/A 0.168±0.00
ENST00000456882 N/A N/A N/A N/A N/A N/A N/A N/A 0.078±0.00 N/A N/A
ENST00000509474 0.309±0.00 N/A 0.274±0.00 N/A 0.237±0.00 N/A 0.336±0.00 N/A 0.193±0.00 N/A 0.299±0.00
ENST00000545647 N/A N/A 0.029±0.00 N/A N/A N/A N/A 0.047±0.00 0.018±0.01 0.020±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00052T CIL_00052T_0002 CGP 4:81030965-81215117
CIL_000086 CIL_000086_0002 CGP 4:81087370-82044244

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004672 TAS:IEA protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004692 IEA cGMP-dependent protein kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005829 TAS cytosol
GO:0005886 IEA plasma membrane
GO:0006468 IEA protein phosphorylation
GO:0007165 TAS signal transduction
GO:0007596 TAS blood coagulation
GO:0007623 IEA circadian rhythm
GO:0016020 IEA membrane
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0030553 IEA cGMP binding
GO:0031965 IEA nuclear membrane
GO:0032922 IEA circadian regulation of gene expression
GO:0036289 IEA peptidyl-serine autophosphorylation
GO:0042803 IEA protein homodimerization activity
GO:0044281 TAS small molecule metabolic process
GO:0046209 TAS nitric oxide metabolic process
GO:0050999 TAS regulation of nitric-oxide synthase activity
GO:0072661 IEA protein targeting to plasma membrane

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000054741 prkg2 protein kinase, cGMP-dependent, type II protein_coding Danio_rerio
ENSMUSG00000029334 Prkg2 protein kinase, cGMP-dependent, type II protein_coding Mus_musculus

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