C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: caspase 6, apoptosis-related cysteine peptidase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000138794 CASP6 9606 - 4:109688622-109703583 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000265164 CASP6-001 109688742-109703473 protein_coding
  ENST00000352981 CASP6-002 109688622-109703419 protein_coding
  ENST00000503684 CASP6-004 109694524-109702849 protein_coding
  ENST00000505117 CASP6-008 109689217-109696495 retained_intron
  ENST00000505486 CASP6-003 109694581-109703583 protein_coding
  ENST00000507550 CASP6-009 109688902-109694589 retained_intron
  ENST00000508203 CASP6-007 109690878-109697779 retained_intron
  ENST00000510324 CASP6-006 109689263-109694701 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000265164ENST00000352981ENST00000505117ENST00000507550ENST00000508203ENST00000510324
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000265164 N/A N/A 1.115±0.00 2.377±0.20 2.935±0.35 0.450±0.00 1.328±1.02 1.760±1.14 1.198±0.00 N/A 4.158±1.05 2.184±0.00 N/A
ENST00000352981 2.769±0.00 N/A 0.579±0.00 2.194±0.00 N/A N/A 1.108±0.73 N/A N/A 0.656±0.00 3.118±2.06 N/A 3.057±0.00
ENST00000505117 N/A 1.677±0.00 N/A N/A 3.231±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000507550 N/A N/A N/A N/A 5.481±0.00 N/A 4.361±0.00 N/A N/A 0.656±0.00 5.191±0.00 N/A N/A
ENST00000508203 N/A 1.971±0.00 N/A N/A 4.786±0.00 N/A 2.439±0.00 4.711±0.00 N/A 1.385±0.00 10.341±0.00 N/A N/A
ENST00000510324 N/A N/A N/A N/A N/A N/A 0.804±0.00 N/A N/A N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004197 IEA:IBA cysteine-type endopeptidase activity
GO:0005515 IPI protein binding
GO:0005654 TAS nucleoplasm
GO:0005829 IDA cytosol
GO:0006508 IEA:IDA proteolysis
GO:0006915 IEA:IBA apoptotic process
GO:0006921 TAS cellular component disassembly involved in execution phase of apoptosis
GO:0008234 TAS:IEA cysteine-type peptidase activity
GO:0030855 IEP epithelial cell differentiation
GO:0042802 IPI identical protein binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000025608 casp6l1 caspase 6, apoptosis-related cysteine peptidase, like 1 protein_coding Danio_rerio
ENSDARG00000093405 casp6 caspase 6, apoptosis-related cysteine peptidase protein_coding Danio_rerio
ENSMUSG00000027997 Casp6 caspase 6 protein_coding Mus_musculus

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