C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cullin 4A
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000139842 CUL4A 9606 + 13:113208193-113267108 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000326335 CUL4A-201 113208694-113265072 protein_coding
  ENST00000375440 CUL4A-002 113209544-113263582 protein_coding
  ENST00000375441 CUL4A-202 113208193-113265072 protein_coding
  ENST00000451881 CUL4A-203 113208772-113265077 protein_coding
  ENST00000463426 CUL4A-004 113209833-113230030 processed_transcript
  ENST00000470067 CUL4A-008 113244223-113254775 processed_transcript
  ENST00000472083 CUL4A-009 113245956-113263559 processed_transcript
  ENST00000474116 CUL4A-006 113209616-113219812 processed_transcript
  ENST00000488558 CUL4A-007 113209600-113230212 protein_coding
  ENST00000494985 CUL4A-003 113209630-113228017 processed_transcript
  ENST00000498562 CUL4A-005 113209883-113235145 processed_transcript
  ENST00000617546 CUL4A-001 113208836-113267108 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000326335ENST00000375440ENST00000375441ENST00000451881ENST00000472083ENST00000498562
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000326335 N/A N/A 2.029±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 7.619±0.00 N/A N/A
ENST00000375440 N/A N/A N/A 2.287±0.00 6.745±0.00 6.358±0.00 9.360±0.00 5.241±0.00 8.850±0.00 4.043±0.00 N/A N/A N/A N/A
ENST00000375441 N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.357±0.00 N/A N/A N/A N/A
ENST00000451881 6.803±0.00 7.164±0.00 N/A 3.800±0.00 8.263±1.62 8.856±4.46 6.542±0.78 6.565±1.07 4.805±1.68 1.955±0.00 11.743±1.98 14.829±6.30 7.422±6.30 22.608±3.79
ENST00000472083 N/A N/A 10.821±0.00 N/A N/A N/A N/A 17.393±0.00 N/A N/A N/A N/A N/A N/A
ENST00000498562 N/A N/A 7.779±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00058J CIL_00058J_0002 CGP 13:113158654-113208715
CIL_0005GG CIL_0005GG_0001 CGP 13:113177539-113267108
CIL_0000QK CIL_0000QK_0001 CGP 13:113208193-113323672

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000082 TAS G1/S transition of mitotic cell cycle
GO:0005515 IPI protein binding
GO:0006281 IEA DNA repair
GO:0006511 IEA ubiquitin-dependent protein catabolic process
GO:0007050 TAS cell cycle arrest
GO:0008284 IEA positive regulation of cell proliferation
GO:0008285 TAS negative regulation of cell proliferation
GO:0016032 IEA viral process
GO:0016567 IEA protein ubiquitination
GO:0030097 IEA hemopoiesis
GO:0030853 IEA negative regulation of granulocyte differentiation
GO:0031461 IEA cullin-RING ubiquitin ligase complex
GO:0031464 IDA Cul4A-RING E3 ubiquitin ligase complex
GO:0031625 IEA ubiquitin protein ligase binding
GO:0035019 IEA somatic stem cell maintenance
GO:0043161 IEA proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051246 IEA regulation of protein metabolic process
GO:0080008 IDA Cul4-RING E3 ubiquitin ligase complex
GO:0097193 TAS intrinsic apoptotic signaling pathway
GO:1900087 IEA positive regulation of G1/S transition of mitotic cell cycle
GO:2000001 IEA regulation of DNA damage checkpoint
GO:2000819 IEA regulation of nucleotide-excision repair

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000024452 cul4a cullin 4A protein_coding Danio_rerio
ENSMUSG00000031446 Cul4a cullin 4A protein_coding Mus_musculus

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