C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: cullin 4A
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000375440 CUL4A-002 ENSG00000139842 9606 + 13:113209544-113263582 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainBreastColonHeartKidneyLiverLungENST00000375440
Transcript ID Brain Breast Colon Heart Kidney Liver Lung
ENST00000375440 2.287±0.00 6.745±0.00 6.358±0.00 9.360±0.00 5.241±0.00 8.850±0.00 4.043±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00058J CIL_00058J_0002 CGP 13:113158654-113208715
CIL_0005GG CIL_0005GG_0001 CGP 13:113177539-113267108
CIL_0000QK CIL_0000QK_0001 CGP 13:113208193-113323672

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000082 TAS G1/S transition of mitotic cell cycle
GO:0005515 IPI protein binding
GO:0006281 IEA DNA repair
GO:0006511 IEA ubiquitin-dependent protein catabolic process
GO:0007050 TAS cell cycle arrest
GO:0008284 IEA positive regulation of cell proliferation
GO:0008285 TAS negative regulation of cell proliferation
GO:0016032 IEA viral process
GO:0016567 IEA protein ubiquitination
GO:0030097 IEA hemopoiesis
GO:0030853 IEA negative regulation of granulocyte differentiation
GO:0031461 IEA cullin-RING ubiquitin ligase complex
GO:0031464 IDA Cul4A-RING E3 ubiquitin ligase complex
GO:0031625 IEA ubiquitin protein ligase binding
GO:0035019 IEA somatic stem cell maintenance
GO:0043161 IEA proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051246 IEA regulation of protein metabolic process
GO:0080008 IDA Cul4-RING E3 ubiquitin ligase complex
GO:0097193 TAS intrinsic apoptotic signaling pathway
GO:1900087 IEA positive regulation of G1/S transition of mitotic cell cycle
GO:2000001 IEA regulation of DNA damage checkpoint
GO:2000819 IEA regulation of nucleotide-excision repair

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000016680 Cul4a-001 protein_coding Mus_musculus 0 2507
ENSMUST00000125514 Cul4a-004 nonsense_mediated_decay Mus_musculus 0 1668
ENSMUST00000121426 Cul4a-002 protein_coding Mus_musculus 0 830
ENSMUST00000135371 Cul4a-003 retained_intron Mus_musculus 0 488
ENSMUST00000125646 Cul4a-006 retained_intron Mus_musculus 0 322
ENSMUST00000142700 Cul4a-005 processed_transcript Mus_musculus 0 313

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