C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: integrin, alpha X (complement component 3 receptor 4 subunit)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000140678 ITGAX 9606 + 16:31355134-31382997 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000268296 ITGAX-001 31355134-31382997 protein_coding
  ENST00000562138 ITGAX-010 31371474-31372654 retained_intron
  ENST00000562522 ITGAX-004 31355222-31382943 protein_coding
  ENST00000562918 ITGAX-003 31355174-31358455 protein_coding
  ENST00000564308 ITGAX-008 31355134-31356278 retained_intron
  ENST00000567409 ITGAX-002 31355188-31357862 retained_intron
  ENST00000571644 ITGAX-005 31359937-31382932 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000268296ENST00000562522ENST00000562918ENST00000567409ENST00000571644
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000268296 1.888±0.00 1.585±0.00 N/A 0.190±0.06 2.316±1.11 0.560±0.00 0.288±0.00 0.640±0.00 N/A 4.949±4.03 N/A 1.410±0.95 1.124±0.15 0.217±0.02
ENST00000562522 N/A N/A N/A 0.265±0.00 N/A N/A N/A N/A N/A N/A N/A 0.385±0.00 N/A 0.112±0.00
ENST00000562918 N/A N/A N/A 0.392±0.00 N/A N/A N/A N/A N/A 7.216±0.00 N/A 0.900±0.00 N/A 0.234±0.00
ENST00000567409 N/A N/A N/A N/A 1.197±0.00 0.418±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000571644 0.650±0.00 1.443±0.00 0.180±0.00 0.110±0.05 0.810±0.00 N/A 0.240±0.00 0.115±0.00 0.142±0.00 2.234±0.00 0.280±0.15 0.568±0.34 0.583±0.17 0.217±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00035O CIL_00035O_0001 CGP 16:31259990-31382997
CIL_00035N CIL_00035N_0001 CGP 16:31355134-31426505

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004872 TAS receptor activity
GO:0005515 IPI protein binding
GO:0005886 TAS plasma membrane
GO:0007155 TAS cell adhesion
GO:0007229 IEA integrin-mediated signaling pathway
GO:0007596 TAS blood coagulation
GO:0008305 IEA integrin complex
GO:0009887 TAS organ morphogenesis
GO:0009897 IEA external side of plasma membrane
GO:0009986 IDA cell surface
GO:0016020 IDA membrane
GO:0030198 TAS extracellular matrix organization
GO:0034113 IMP heterotypic cell-cell adhesion
GO:0046872 IEA metal ion binding
GO:0050900 TAS leukocyte migration
GO:0051607 IEA defense response to virus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000002956 ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) protein_coding Danio_rerio
ENSMUSG00000030789 Itgax integrin alpha X protein_coding Mus_musculus

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