C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: transforming growth factor beta 1 induced transcript 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000140682 TGFB1I1 9606 + 16:31471585-31477960 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000361773 TGFB1I1-201 31472208-31477960 protein_coding
  ENST00000394858 TGFB1I1-002 31473205-31477960 protein_coding
  ENST00000394863 TGFB1I1-001 31472059-31477958 protein_coding
  ENST00000561785 TGFB1I1-017 31472155-31474095 retained_intron
  ENST00000562165 TGFB1I1-018 31472171-31474100 retained_intron
  ENST00000562566 TGFB1I1-015 31473080-31473972 protein_coding
  ENST00000563712 TGFB1I1-007 31472154-31477600 nonsense_mediated_decay
  ENST00000564176 TGFB1I1-003 31472171-31477958 retained_intron
  ENST00000564804 TGFB1I1-005 31473440-31477906 nonsense_mediated_decay
  ENST00000565360 TGFB1I1-020 31472168-31474759 protein_coding
  ENST00000565454 TGFB1I1-012 31471585-31474590 protein_coding
  ENST00000567066 TGFB1I1-006 31472030-31477600 nonsense_mediated_decay
  ENST00000567524 TGFB1I1-016 31472141-31473939 retained_intron
  ENST00000567607 TGFB1I1-004 31473426-31477958 protein_coding
  ENST00000568142 TGFB1I1-019 31473434-31476802 retained_intron
  ENST00000569254 TGFB1I1-014 31472157-31474239 retained_intron
  ENST00000569703 TGFB1I1-021 31472175-31476288 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000361773ENST00000394863ENST00000562165ENST00000562566ENST00000564176ENST00000564804ENST00000565360ENST00000565454ENST00000567066ENST00000567524ENST00000567607ENST00000568142ENST00000569703
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000361773 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 71.840±0.00 33.848±0.00 0.442±0.00
ENST00000394863 9.331±0.00 N/A N/A N/A 14.801±0.00 54.727±0.00 4.672±0.00 3.317±0.00 N/A 23.410±0.00 4.797±0.00 40.242±38.54 9.965±2.18 33.457±0.00
ENST00000562165 N/A N/A N/A N/A N/A N/A 0.465±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000562566 N/A N/A 2.157±0.00 N/A N/A N/A N/A N/A N/A 2.001±0.00 N/A N/A N/A N/A
ENST00000564176 N/A N/A N/A 0.020±0.00 N/A N/A N/A N/A 0.978±0.00 0.135±0.00 N/A 0.068±0.00 N/A N/A
ENST00000564804 8.215±0.00 16.347±0.00 N/A N/A 14.375±0.00 17.977±0.00 N/A N/A N/A N/A N/A 4.299±0.00 15.181±0.00 2.201±0.00
ENST00000565360 13.272±0.00 N/A N/A 1.626±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000565454 N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.875±0.00 N/A 2.804±0.00 N/A N/A
ENST00000567066 12.193±0.00 18.262±0.00 N/A 1.195±0.00 1.196±0.00 29.554±0.00 N/A N/A N/A N/A N/A 46.119±0.00 N/A 18.939±0.00
ENST00000567524 N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.330±0.00 N/A N/A N/A N/A
ENST00000567607 9.802±0.00 33.034±0.00 N/A N/A 1.130±0.00 0.322±0.00 4.950±0.00 12.536±0.00 6.659±4.36 34.496±0.00 3.124±1.74 34.298±0.00 55.924±0.00 0.467±0.00
ENST00000568142 N/A N/A N/A 0.155±0.02 0.645±0.00 N/A N/A 1.496±0.00 N/A N/A N/A 0.069±0.00 N/A N/A
ENST00000569703 N/A N/A N/A N/A N/A N/A 0.170±0.00 N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00090H CIL_00090H_0001 VISTA 16:31421736-32023283
CIL_00035P CIL_00035P_0001 CGP 16:31458080-31477960
CIL_000708 CIL_000708_0001 CGP 16:31471585-31490860

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003713 IDA transcription coactivator activity
GO:0005515 IPI protein binding
GO:0005622 IDA intracellular
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005856 IEA cytoskeleton
GO:0005925 IDA focal adhesion
GO:0006366 TAS transcription from RNA polymerase II promoter
GO:0007155 TAS cell adhesion
GO:0008270 IEA zinc ion binding
GO:0008285 TAS negative regulation of cell proliferation
GO:0009408 IEA response to heat
GO:0010718 IDA positive regulation of epithelial to mesenchymal transition
GO:0016055 IEA Wnt signaling pathway
GO:0016331 IEA morphogenesis of embryonic epithelium
GO:0030511 IDA positive regulation of transforming growth factor beta receptor signaling pathway
GO:0030512 IDA negative regulation of transforming growth factor beta receptor signaling pathway
GO:0030521 NAS androgen receptor signaling pathway
GO:0030579 IDA ubiquitin-dependent SMAD protein catabolic process
GO:0030855 IEA epithelial cell differentiation
GO:0031012 IDA extracellular matrix
GO:0045165 IEA cell fate commitment
GO:0045599 IEA negative regulation of fat cell differentiation
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0048495 IPI Roundabout binding
GO:0050681 IPI androgen receptor binding
GO:0070411 IPI I-SMAD binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000030782 Tgfb1i1 transforming growth factor beta 1 induced transcript 1 protein_coding Mus_musculus

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