C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: transforming growth factor beta 1 induced transcript 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000030782 Tgfb1i1 10090 + 7:128246812-128253712 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000070656 Tgfb1i1-002 128246871-128253712 protein_coding
  ENSMUST00000163553 Tgfb1i1-007 128248018-128253711 retained_intron
  ENSMUST00000163609 Tgfb1i1-005 128248018-128253711 protein_coding
  ENSMUST00000164710 Tgfb1i1-001 128246812-128253711 protein_coding
  ENSMUST00000165667 Tgfb1i1-010 128248018-128253711 protein_coding
  ENSMUST00000166755 Tgfb1i1-008 128248018-128253711 retained_intron
  ENSMUST00000167965 Tgfb1i1-003 128246978-128253707 protein_coding
  ENSMUST00000168825 Tgfb1i1-006 128248018-128253711 protein_coding
  ENSMUST00000169919 Tgfb1i1-004 128246961-128253404 nonsense_mediated_decay
  ENSMUST00000170115 Tgfb1i1-011 128248176-128253366 nonsense_mediated_decay
  ENSMUST00000171888 Tgfb1i1-009 128248018-128253711 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000070656ENSMUST00000163553ENSMUST00000164710ENSMUST00000165667ENSMUST00000166755ENSMUST00000167965ENSMUST00000169919ENSMUST00000170115
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000070656 7.907±4.08 1.084±0.12 8.134±2.31 0.568±0.19 2.218±0.08 N/A 1.307±0.10 0.611±0.12 0.401±0.23 4.755±0.19 0.481±0.12 7.156±0.94 1.067±0.39 0.301±0.19
ENSMUST00000163553 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.556±0.00 N/A
ENSMUST00000164710 4.798±0.29 2.174±0.58 20.345±6.81 1.099±0.57 3.082±0.47 6.819±0.46 2.778±0.79 2.079±0.62 0.550±0.35 14.453±0.65 0.694±0.13 8.168±0.00 1.215±0.77 0.348±0.23
ENSMUST00000165667 N/A N/A N/A N/A N/A N/A N/A N/A 0.175±0.00 N/A N/A N/A 1.211±0.66 N/A
ENSMUST00000166755 N/A N/A N/A N/A N/A N/A N/A N/A 0.180±0.00 N/A 0.446±0.00 N/A N/A N/A
ENSMUST00000167965 37.896±21.76 3.106±0.82 79.624±21.44 3.255±1.09 10.896±3.07 23.597±1.19 5.365±0.98 3.511±0.74 2.206±1.71 30.192±0.86 1.903±0.32 33.040±12.42 6.452±4.35 1.236±0.09
ENSMUST00000169919 N/A 6.679±1.01 N/A N/A 8.420±2.29 15.347±3.33 N/A N/A 0.198±0.04 N/A N/A 25.421±4.62 N/A N/A
ENSMUST00000170115 N/A 2.628±0.43 N/A N/A N/A N/A N/A N/A N/A N/A N/A 16.107±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00035P CIL_00035P_0002 CGP 7:128237357-128253712
CIL_000708 CIL_000708_0002 CGP 7:128246812-128272430

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003713 IEA transcription coactivator activity
GO:0005515 IPI protein binding
GO:0005622 IEA intracellular
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005856 IEA cytoskeleton
GO:0005925 IDA focal adhesion
GO:0008270 IEA zinc ion binding
GO:0009408 IEA response to heat
GO:0010718 IEA positive regulation of epithelial to mesenchymal transition
GO:0016055 IEA Wnt signaling pathway
GO:0016331 IMP morphogenesis of embryonic epithelium
GO:0030511 IEA positive regulation of transforming growth factor beta receptor signaling pathway
GO:0030512 IEA negative regulation of transforming growth factor beta receptor signaling pathway
GO:0030579 IEA ubiquitin-dependent SMAD protein catabolic process
GO:0030855 IGI epithelial cell differentiation
GO:0031012 IEA extracellular matrix
GO:0045165 IGI cell fate commitment
GO:0045599 IGI negative regulation of fat cell differentiation
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0048495 IEA Roundabout binding
GO:0050681 IEA androgen receptor binding
GO:0070411 IEA I-SMAD binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000140682 TGFB1I1 transforming growth factor beta 1 induced transcript 1 protein_coding Homo_sapiens

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