C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: zinc finger homeobox 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000140836 ZFHX3 9606 - 16:72782885-73059698 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000268489 ZFHX3-001 72782885-73048375 protein_coding
  ENST00000397992 ZFHX3-002 72782885-73059698 protein_coding
  ENST00000558842 ZFHX3-004 73058881-73059222 processed_transcript
  ENST00000563625 ZFHX3-003 72829509-72889834 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000268489ENST00000397992
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000268489 2.846±0.00 1.535±0.00 0.574±0.00 0.467±0.19 2.931±0.00 1.923±0.62 0.941±0.58 1.264±0.27 0.396±0.00 1.136±0.04 2.810±1.01 1.031±0.48 1.095±0.49 1.211±0.73
ENST00000397992 1.459±0.00 0.340±0.00 0.520±0.00 0.356±0.24 1.332±0.00 1.257±0.47 0.573±0.39 1.088±0.00 0.557±0.07 1.489±0.41 4.108±0.00 0.990±0.64 2.001±1.82 0.878±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000858 CIL_000858_0001 VISTA 16:72289766-72891318
CIL_0007KL CIL_0007KL_0001 UCNEbase 16:72373211-73946064
CIL_00099L CIL_00099L_0001 VISTA 16:72400827-73001726
CIL_00098C CIL_00098C_0001 VISTA 16:72404669-73006250
CIL_0008IG CIL_0008IG_0001 VISTA 16:72505663-73107225
CIL_0008IF CIL_0008IF_0001 VISTA 16:72553694-73154614
CIL_0008I9 CIL_0008I9_0001 VISTA 16:72595979-73197389
CIL_0008I8 CIL_0008I8_0001 VISTA 16:72647001-73248646

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IGI negative regulation of transcription from RNA polymerase II promoter
GO:0003676 IEA nucleic acid binding
GO:0003677 IEA DNA binding
GO:0003700 NAS sequence-specific DNA binding transcription factor activity
GO:0003705 TAS RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0003779 IEA actin binding
GO:0005634 TAS nucleus
GO:0005667 IDA transcription factor complex
GO:0005737 IEA cytoplasm
GO:0005739 IEA mitochondrion
GO:0006355 TAS regulation of transcription, DNA-templated
GO:0006366 TAS transcription from RNA polymerase II promoter
GO:0007010 IEA cytoskeleton organization
GO:0007050 IEA cell cycle arrest
GO:0007420 IEA brain development
GO:0007517 IEA muscle organ development
GO:0008270 IEA zinc ion binding
GO:0019899 IPI enzyme binding
GO:0043565 IEA sequence-specific DNA binding
GO:0044212 IDA transcription regulatory region DNA binding
GO:0045662 IDA negative regulation of myoblast differentiation
GO:0045663 IDA positive regulation of myoblast differentiation
GO:0045664 IEA regulation of neuron differentiation
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000073681 zfhx3 zinc finger homeobox 3 protein_coding Danio_rerio
ENSDARG00000073944 ZFHX3 (2 of 2) zinc finger homeobox 3 protein_coding Danio_rerio
ENSMUSG00000038872 Zfhx3 zinc finger homeobox 3 protein_coding Mus_musculus

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