C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: tubulin folding cofactor D
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000141556 TBCD 9606 + 17:82752064-82942848 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000355528 TBCD-001 82752064-82942848 protein_coding
  ENST00000539345 TBCD-005 82752158-82942709 protein_coding
  ENST00000570679 TBCD-022 82926866-82929259 retained_intron
  ENST00000571316 TBCD-006 82884152-82914153 protein_coding
  ENST00000571618 TBCD-019 82908277-82927311 processed_transcript
  ENST00000571712 TBCD-011 82858596-82921576 protein_coding
  ENST00000571796 TBCD-007 82895825-82929791 retained_intron
  ENST00000572389 TBCD-029 82939042-82942704 retained_intron
  ENST00000572794 TBCD-009 82939401-82942702 protein_coding
  ENST00000572953 TBCD-017 82893108-82921575 protein_coding
  ENST00000572984 TBCD-015 82886084-82911765 protein_coding
  ENST00000573364 TBCD-026 82932687-82937847 retained_intron
  ENST00000574422 TBCD-018 82900542-82926439 protein_coding
  ENST00000574801 TBCD-012 82864291-82911789 processed_transcript
  ENST00000574818 TBCD-020 82920460-82929132 retained_intron
  ENST00000574886 TBCD-021 82921016-82927213 retained_intron
  ENST00000574975 TBCD-016 82893064-82925056 protein_coding
  ENST00000575132 TBCD-024 82930458-82941433 retained_intron
  ENST00000576160 TBCD-010 82858519-82921510 protein_coding
  ENST00000576432 TBCD-027 82937216-82942704 retained_intron
  ENST00000576603 TBCD-025 82931949-82942571 processed_transcript
  ENST00000576677 TBCD-008 82929425-82942704 retained_intron
  ENST00000576691 TBCD-028 82937570-82942704 processed_transcript
  ENST00000576760 TBCD-014 82884801-82926476 protein_coding
  ENST00000576996 TBCD-013 82860394-82920606 protein_coding
  ENST00000577051 TBCD-023 82929138-82942659 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000355528ENST00000539345ENST00000572953ENST00000574818ENST00000576160ENST00000576996ENST00000577051
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000355528 5.982±0.00 8.035±0.00 0.749±0.00 4.233±1.73 2.308±0.00 3.000±1.28 2.078±1.55 3.534±2.84 3.173±1.63 1.326±0.00 2.888±0.00 8.644±5.11 13.655±6.29 9.071±2.35
ENST00000539345 5.644±0.00 4.575±0.00 N/A 7.990±0.00 10.495±0.00 4.878±0.00 5.851±0.00 3.429±0.00 4.179±0.00 5.637±0.00 4.911±0.00 N/A N/A 10.617±3.34
ENST00000572953 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 21.169±0.00 N/A
ENST00000574818 16.078±0.00 N/A N/A N/A N/A 4.607±0.00 N/A N/A N/A N/A 5.606±0.00 N/A 16.062±0.00 N/A
ENST00000576160 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 5.259±0.00 N/A N/A
ENST00000576996 N/A N/A N/A N/A N/A 5.680±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000577051 18.806±0.00 28.312±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00043Z CIL_00043Z_0002 CGP 17:82735575-82942848
CIL_00025M CIL_00025M_0002 CGP 17:82752064-82942848

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005096 IMP GTPase activator activity
GO:0005488 IEA binding
GO:0005515 IPI protein binding
GO:0005737 IEA cytoplasm
GO:0005874 TAS microtubule
GO:0005912 ISS adherens junction
GO:0005923 ISS tight junction
GO:0006457 IDA protein folding
GO:0007023 IDA post-chaperonin tubulin folding pathway
GO:0010812 ISS negative regulation of cell-substrate adhesion
GO:0016328 ISS lateral plasma membrane
GO:0031115 IDA negative regulation of microtubule polymerization
GO:0034333 ISS adherens junction assembly
GO:0043547 IEA positive regulation of GTPase activity
GO:0044267 TAS cellular protein metabolic process
GO:0048487 IDA beta-tubulin binding
GO:0051084 TAS 'de novo' posttranslational protein folding
GO:0051087 TAS chaperone binding
GO:0070830 ISS tight junction assembly

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000040099 tbcd tubulin-specific chaperone d protein_coding Danio_rerio
ENSMUSG00000039230 Tbcd tubulin-specific chaperone d protein_coding Mus_musculus

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