C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: interferon induced transmembrane protein 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000142089 IFITM3 9606 - 11:319669-327537 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000399808 IFITM3-001 319669-321050 protein_coding
  ENST00000526811 IFITM3-002 319773-321340 protein_coding
  ENST00000531688 IFITM3-003 319746-320683 nonsense_mediated_decay
  ENST00000602735 IFITM3-004 319773-327537 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000399808ENST00000526811
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000399808 527.862±0.00 654.303±0.00 4.912±0.00 72.549±67.90 89.765±82.47 273.561±269.12 38.652±35.06 182.530±139.19 198.142±192.08 242.970±231.89 28.277±16.74 167.419±143.16 559.676±368.16 195.193±173.80
ENST00000526811 N/A N/A N/A N/A 2.365±0.00 N/A 41.254±0.00 N/A N/A N/A 27.674±0.00 189.316±47.94 386.271±121.09 49.143±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002UG CIL_0002UG_0002 CGP 11:313506-327537

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005764 IEA lysosome
GO:0005768 IEA endosome
GO:0005886 IDA plasma membrane
GO:0006955 TAS immune response
GO:0009607 IEA response to biotic stimulus
GO:0009615 IDA response to virus
GO:0016021 IEA integral component of membrane
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0032897 IDA negative regulation of viral transcription
GO:0034341 IDA response to interferon-gamma
GO:0035455 IDA response to interferon-alpha
GO:0035456 IDA response to interferon-beta
GO:0045071 IDA negative regulation of viral genome replication
GO:0046597 IDA negative regulation of viral entry into host cell
GO:0051607 IEA defense response to virus
GO:0060337 TAS type I interferon signaling pathway
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000093303 si:dkey-226m8.7 interferon induced transmembrane protein 3 protein_coding Danio_rerio
ENSMUSG00000025491 Ifitm1 interferon induced transmembrane protein 1 protein_coding Mus_musculus
ENSMUSG00000025492 Ifitm3 interferon induced transmembrane protein 3 protein_coding Mus_musculus
ENSMUSG00000060591 Ifitm2 interferon induced transmembrane protein 2 protein_coding Mus_musculus
ENSMUSG00000065968 Ifitm7 interferon induced transmembrane protein 7 protein_coding Mus_musculus
ENSMUSG00000068631 Gm7676 predicted gene 7676 protein_coding Mus_musculus

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