Institute of Cardiovascular Regeneration Webtool Repository

C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Accession	Transcript Name	Contained in Gene	Tax ID	Strand	Position	Biotype
Transcript Info
Description:	interferon induced transmembrane protein 3
ENST00000399808	IFITM3-001	ENSG00000142089	9606	-	11:319669-321050	protein_coding

Expression Patterns

Transcript ID	Adipose	Adrenal	Bladder	Brain	Breast	Colon	Heart	Kidney	Liver	Lung	Muscle	Ovary	Placenta	Testis
ENST00000399808	527.862±0.00	654.303±0.00	4.912±0.00	72.549±67.90	89.765±82.47	273.561±269.12	38.652±35.06	182.530±139.19	198.142±192.08	242.970±231.89	28.277±16.74	167.419±143.16	559.676±368.16	195.193±173.80

Conserved Regions
Region ID	Sub-Region	Region Type	Position
CIL_0002UG	CIL_0002UG_0002	CGP	11:313506-327537

Gene Ontology
GO ID	Evidence Type	GO Description
GO:0005515	IPI	protein binding
GO:0005764	IEA	lysosome
GO:0005768	IEA	endosome
GO:0005886	IDA	plasma membrane
GO:0006955	TAS	immune response
GO:0009607	IEA	response to biotic stimulus
GO:0009615	IDA	response to virus
GO:0016021	IEA	integral component of membrane
GO:0019221	TAS	cytokine-mediated signaling pathway
GO:0032897	IDA	negative regulation of viral transcription
GO:0034341	IDA	response to interferon-gamma
GO:0035455	IDA	response to interferon-alpha
GO:0035456	IDA	response to interferon-beta
GO:0045071	IDA	negative regulation of viral genome replication
GO:0046597	IDA	negative regulation of viral entry into host cell
GO:0051607	IEA	defense response to virus
GO:0060337	TAS	type I interferon signaling pathway
GO:0070062	IDA	extracellular vesicular exosome

Homologs
ENSEMBL Accession	Gene Name	Biotype	Species	E-Value	Bit Score
ENSMUST00000026564	Ifitm1-003	protein_coding	Mus_musculus	0	228
ENSMUST00000106040	Ifitm1-002	protein_coding	Mus_musculus	0	228
ENSMUST00000106042	Ifitm1-001	protein_coding	Mus_musculus	0	228

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