C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: interferon (alpha, beta and omega) receptor 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000142166 IFNAR1 9606 + 21:33324477-33359862 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000270139 IFNAR1-001 33324904-33359862 protein_coding
  ENST00000442071 IFNAR1-003 33324973-33345277 protein_coding
  ENST00000493503 IFNAR1-002 33324477-33335611 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000270139
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000270139 14.932±0.00 7.160±0.00 3.708±0.00 4.870±1.79 7.614±2.86 6.946±3.67 3.111±1.96 7.299±0.12 8.418±2.84 8.318±2.39 1.693±0.75 5.331±0.89 9.506±1.96 5.238±2.08

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007UY CIL_0007UY_0001 VISTA 21:32793653-33396760
CIL_0007I0 CIL_0007I0_0001 CGP 21:33266358-33359862
CIL_0003WY CIL_0003WY_0001 CGP 21:33324477-33479348

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004904 IEA interferon receptor activity
GO:0004905 TAS type I interferon receptor activity
GO:0005515 IPI:IEA protein binding
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0007166 TAS cell surface receptor signaling pathway
GO:0007259 TAS JAK-STAT cascade
GO:0009615 TAS response to virus
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0032729 IEA positive regulation of interferon-gamma production
GO:0042110 IEA T cell activation
GO:0045351 IEA type I interferon biosynthetic process
GO:0050718 IEA positive regulation of interleukin-1 beta secretion
GO:0051607 IEA defense response to virus
GO:0060337 TAS type I interferon signaling pathway
GO:0060338 TAS regulation of type I interferon-mediated signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000078042 crfb5 cytokine receptor family member b5 protein_coding Danio_rerio
ENSMUSG00000022967 Ifnar1 interferon (alpha and beta) receptor 1 protein_coding Mus_musculus

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