C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: salt-inducible kinase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000142178 SIK1 9606 - 21:43414515-43427128 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000270162 SIK1-001 43414515-43427128 protein_coding
  ENST00000478426 SIK1-002 43421112-43422005 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000270162ENST00000478426
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000270162 3.984±0.00 0.480±0.00 0.199±0.00 0.119±0.00 0.069±0.00 0.037±0.03 0.225±0.14 0.073±0.00 0.115±0.02 0.599±0.52 0.064±0.00 1.553±1.71 0.518±0.60 0.347±0.00
ENST00000478426 N/A N/A N/A 0.157±0.00 0.317±0.07 0.043±0.00 N/A 0.095±0.00 0.162±0.00 N/A N/A 0.637±0.28 0.105±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001M3 CIL_0001M3_0001 CGP 21:43169008-43427128
CIL_000617 CIL_000617_0001 CGP 21:43414515-43659493

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000287 ISS:IEA magnesium ion binding
GO:0002028 ISS regulation of sodium ion transport
GO:0004672 IEA protein kinase activity
GO:0004674 IDA:IEA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 ISS:IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 ISS cytoplasm
GO:0006468 ISS:IEA protein phosphorylation
GO:0007049 IEA cell cycle
GO:0007346 ISS regulation of mitotic cell cycle
GO:0008140 ISS cAMP response element binding protein binding
GO:0010830 ISS regulation of myotube differentiation
GO:0010868 ISS negative regulation of triglyceride biosynthetic process
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0019901 IPI protein kinase binding
GO:0032792 ISS negative regulation of CREB transcription factor activity
GO:0035556 ISS:IEA intracellular signal transduction
GO:0043153 ISS entrainment of circadian clock by photoperiod
GO:0045595 ISS regulation of cell differentiation
GO:0045721 ISS negative regulation of gluconeogenesis
GO:0046777 IDA protein autophosphorylation
GO:0055007 ISS cardiac muscle cell differentiation
GO:0071889 IDA 14-3-3 protein binding
GO:2000210 IMP positive regulation of anoikis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000058606 SIK1 salt-inducible kinase 1 protein_coding Danio_rerio
ENSMUSG00000024042 Sik1 salt inducible kinase 1 protein_coding Mus_musculus

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