C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: salt inducible kinase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000024042 Sik1 10090 - 17:31844248-31855792 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000024839 Sik1-201 31844248-31855792 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000024839
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000024839 11.129±4.53 10.059±4.04 11.033±5.63 3.322±1.69 15.494±6.75 6.079±0.28 4.726±2.13 16.611±3.91 3.144±1.11 31.495±8.34 2.247±0.49 12.038±2.92 8.437±1.00 5.103±3.27

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001M3 CIL_0001M3_0002 CGP 17:31677933-31855792
CIL_000617 CIL_000617_0002 CGP 17:31844248-32034508

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000287 IDA magnesium ion binding
GO:0002028 ISS regulation of sodium ion transport
GO:0004674 IDA protein serine/threonine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IDA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 IEA cytosol
GO:0006468 IDA protein phosphorylation
GO:0007049 IEA cell cycle
GO:0007346 IDA regulation of mitotic cell cycle
GO:0008140 IDA cAMP response element binding protein binding
GO:0010830 IDA regulation of myotube differentiation
GO:0010868 IDA negative regulation of triglyceride biosynthetic process
GO:0019901 IPI protein kinase binding
GO:0032792 IDA negative regulation of CREB transcription factor activity
GO:0035556 IDA intracellular signal transduction
GO:0042826 IPI histone deacetylase binding
GO:0043153 IMP entrainment of circadian clock by photoperiod
GO:0043276 IMP anoikis
GO:0045595 IEP regulation of cell differentiation
GO:0045721 IDA negative regulation of gluconeogenesis
GO:0046777 ISS protein autophosphorylation
GO:0055007 IMP cardiac muscle cell differentiation
GO:0071889 ISS 14-3-3 protein binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000058606 SIK1 salt-inducible kinase 1 protein_coding Danio_rerio
ENSG00000142178 SIK1 salt-inducible kinase 1 protein_coding Homo_sapiens
ENSG00000275993 CH507-42P11.8 protein_coding Homo_sapiens

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