C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: proteasome (prosome, macropain) subunit, alpha type, 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000143106 PSMA5 9606 - 1:109399031-109426427 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000271308 PSMA5-001 109399031-109426351 protein_coding
  ENST00000477897 PSMA5-005 109411870-109412285 processed_transcript
  ENST00000484563 PSMA5-003 109411953-109426427 processed_transcript
  ENST00000490870 PSMA5-002 109401850-109426132 processed_transcript
  ENST00000491287 PSMA5-004 109414809-109415365 processed_transcript
  ENST00000538610 PSMA5-201 109402013-109426132 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000271308ENST00000484563ENST00000490870ENST00000538610
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000271308 N/A N/A 1.179±0.00 6.573±0.91 N/A 0.633±0.00 N/A 2.370±0.13 1.306±0.69 0.719±0.00 1.075±0.00 1.151±0.44 N/A 0.353±0.00
ENST00000484563 4.392±0.00 3.079±0.00 N/A N/A 3.559±0.00 2.933±0.11 1.483±0.00 3.275±0.00 2.732±0.00 4.242±0.00 2.171±0.95 4.281±1.58 4.284±0.56 5.638±0.59
ENST00000490870 11.732±0.00 13.861±0.00 N/A 5.848±0.75 13.861±0.00 6.760±5.41 7.776±4.95 13.439±7.34 13.383±9.18 11.444±4.41 8.112±3.71 6.072±3.50 22.675±2.74 11.012±9.19
ENST00000538610 N/A N/A 3.553±0.00 N/A 2.124±0.00 N/A N/A 2.531±0.00 N/A N/A N/A 4.208±0.57 N/A 2.069±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00098X CIL_00098X_0001 VISTA 1:108953074-109556228
CIL_00099A CIL_00099A_0001 VISTA 1:108974252-109576283
CIL_000734 CIL_000734_0002 CGP 1:109309568-109426427
CIL_000735 CIL_000735_0002 CGP 1:109399031-109482137

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000082 TAS G1/S transition of mitotic cell cycle
GO:0000209 TAS protein polyubiquitination
GO:0000278 TAS mitotic cell cycle
GO:0000502 IDA proteasome complex
GO:0002474 TAS antigen processing and presentation of peptide antigen via MHC class I
GO:0002479 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0004175 IEA endopeptidase activity
GO:0004298 IEA threonine-type endopeptidase activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0005839 ISS:IEA proteasome core complex
GO:0006511 IEA ubiquitin-dependent protein catabolic process
GO:0006521 TAS regulation of cellular amino acid metabolic process
GO:0006915 TAS apoptotic process
GO:0006977 TAS DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0010467 TAS gene expression
GO:0016032 TAS viral process
GO:0016070 TAS RNA metabolic process
GO:0016071 TAS mRNA metabolic process
GO:0019773 IEA proteasome core complex, alpha-subunit complex
GO:0031145 TAS anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0042590 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0042981 TAS regulation of apoptotic process
GO:0043066 TAS negative regulation of apoptotic process
GO:0044281 TAS small molecule metabolic process
GO:0051436 TAS negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051437 TAS positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051439 TAS regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051603 IEA proteolysis involved in cellular protein catabolic process
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000003526 psma5 proteasome (prosome, macropain) subunit, alpha type,5 protein_coding Danio_rerio
ENSMUSG00000050490 Gm8394 predicted gene 8394 protein_coding Mus_musculus
ENSMUSG00000068749 Psma5 proteasome (prosome, macropain) subunit, alpha type 5 protein_coding Mus_musculus

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