C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ATP-binding cassette, sub-family G (WHITE), member 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000143921 ABCG8 9606 + 2:43838964-43878466 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000272286 ABCG8-001 43838964-43878466 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastColonKidneyLiverOvaryTestisENST00000272286
Transcript ID Adrenal Bladder Brain Breast Colon Kidney Liver Ovary Testis
ENST00000272286 0.008±0.00 0.222±0.00 0.139±0.03 0.008±0.00 0.117±0.00 6.086±0.00 10.892±0.00 0.018±0.00 0.086±0.01

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001XO CIL_0001XO_0001 CGP 2:43812472-43878466
CIL_0001XN CIL_0001XN_0001 CGP 2:43838964-43996005

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005524 IDA:IEA ATP binding
GO:0005886 TAS plasma membrane
GO:0006200 IEA ATP catabolic process
GO:0007584 IEA response to nutrient
GO:0007588 IGI excretion
GO:0010949 IMP negative regulation of intestinal phytosterol absorption
GO:0015248 IEA sterol transporter activity
GO:0015914 IEA phospholipid transport
GO:0015918 TAS sterol transport
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0016324 IMP apical plasma membrane
GO:0016887 IDA:IEA ATPase activity
GO:0017127 IGI cholesterol transporter activity
GO:0030299 IC intestinal cholesterol absorption
GO:0033344 IGI cholesterol efflux
GO:0042493 IEA response to drug
GO:0042632 IMP cholesterol homeostasis
GO:0044281 TAS small molecule metabolic process
GO:0045796 IMP negative regulation of intestinal cholesterol absorption
GO:0046982 IPI protein heterodimerization activity
GO:0055085 TAS transmembrane transport
GO:0055092 IEA sterol homeostasis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000063059 abcg8 ATP-binding cassette, sub-family G (WHITE), member 8 protein_coding Danio_rerio
ENSMUSG00000024254 Abcg8 ATP-binding cassette, sub-family G (WHITE), member 8 protein_coding Mus_musculus

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