C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ATP-binding cassette, sub-family G (WHITE), member 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000024254 Abcg8 10090 + 17:84676302-84700333 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000045714 Abcg8-001 84683121-84700333 protein_coding
  ENSMUST00000170725 Abcg8-002 84676302-84699333 protein_coding
  ENSMUST00000171915 Abcg8-003 84683131-84698963 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000045714ENSMUST00000170725ENSMUST00000171915
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000045714 0.027±0.00 0.084±0.00 N/A 0.168±0.00 0.079±0.02 0.721±0.02 0.018±0.00 0.060±0.01 12.430±6.84 0.028±0.01 0.008±0.00 0.056±0.03 0.012±0.00 N/A
ENSMUST00000170725 0.052±0.03 0.066±0.03 N/A 0.013±0.00 0.104±0.04 1.183±0.48 N/A 0.095±0.04 0.202±0.01 N/A N/A N/A 0.227±0.00 1.082±0.68
ENSMUST00000171915 0.010±0.00 N/A 0.052±0.00 N/A 0.051±0.03 1.773±0.72 N/A 0.213±0.00 25.288±14.34 0.080±0.00 N/A 0.096±0.07 0.095±0.10 1.249±0.31

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001XP CIL_0001XP_0002 CGP 17:84626496-84683011
CIL_0001XO CIL_0001XO_0002 CGP 17:84658234-84700333
CIL_0001XN CIL_0001XN_0002 CGP 17:84676302-84790789

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0006200 IEA ATP catabolic process
GO:0007584 IEA response to nutrient
GO:0007588 IMP excretion
GO:0010949 IEA negative regulation of intestinal phytosterol absorption
GO:0015248 IEA sterol transporter activity
GO:0015914 IMP phospholipid transport
GO:0015918 IMP sterol transport
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0016324 IMP apical plasma membrane
GO:0016887 IEA ATPase activity
GO:0017127 IMP cholesterol transporter activity
GO:0030299 IC intestinal cholesterol absorption
GO:0033344 IMP cholesterol efflux
GO:0042493 IEA response to drug
GO:0042632 IMP cholesterol homeostasis
GO:0045796 IEA negative regulation of intestinal cholesterol absorption
GO:0046982 IEA protein heterodimerization activity
GO:0055092 IMP sterol homeostasis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000063059 abcg8 ATP-binding cassette, sub-family G (WHITE), member 8 protein_coding Danio_rerio
ENSG00000143921 ABCG8 ATP-binding cassette, sub-family G (WHITE), member 8 protein_coding Homo_sapiens

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