C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cholinergic receptor, nicotinic, alpha 6 (neuronal)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000147434 CHRNA6 9606 - 8:42752620-42796392 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000276410 CHRNA6-001 42752620-42768786 protein_coding
  ENST00000529467 CHRNA6-002 42764973-42768648 retained_intron
  ENST00000530869 CHRNA6-003 42756940-42768632 processed_transcript
  ENST00000533810 CHRNA6-005 42756629-42796392 protein_coding
  ENST00000534622 CHRNA6-004 42752927-42768610 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainBreastLungMuscleOvaryPlacentaTestisENST00000276410ENST00000529467ENST00000530869ENST00000533810ENST00000534622
Transcript ID Adrenal Brain Breast Lung Muscle Ovary Placenta Testis
ENST00000276410 N/A N/A N/A N/A N/A 0.057±0.04 0.013±0.00 N/A
ENST00000529467 N/A N/A N/A N/A N/A 0.117±0.00 N/A 0.068±0.00
ENST00000530869 N/A N/A 0.053±0.00 N/A N/A N/A N/A 0.062±0.00
ENST00000533810 N/A 0.102±0.00 N/A 0.024±0.00 N/A N/A N/A N/A
ENST00000534622 0.007±0.00 0.146±0.05 0.023±0.00 N/A 0.023±0.00 0.021±0.00 0.022±0.00 0.035±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002IT CIL_0002IT_0001 CGP 8:42697376-42796392

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004889 IEA acetylcholine-activated cation-selective channel activity
GO:0005230 IEA extracellular ligand-gated ion channel activity
GO:0005515 IEA protein binding
GO:0005886 TAS plasma membrane
GO:0005892 IEA acetylcholine-gated channel complex
GO:0006810 TAS:IEA transport
GO:0006811 IEA ion transport
GO:0006812 TAS cation transport
GO:0007165 TAS signal transduction
GO:0007268 TAS synaptic transmission
GO:0014059 IEA regulation of dopamine secretion
GO:0015464 TAS acetylcholine receptor activity
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0030054 IEA cell junction
GO:0045211 IEA postsynaptic membrane
GO:0051899 IEA membrane depolarization
GO:0098655 IEA cation transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000055559 chrna6 cholinergic receptor, nicotinic, alpha 6 protein_coding Danio_rerio
ENSMUSG00000031491 Chrna6 cholinergic receptor, nicotinic, alpha polypeptide 6 protein_coding Mus_musculus

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