C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000147854 UHRF2 9606 + 9:6413151-6507054 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000276893 UHRF2-003 6413323-6507054 protein_coding
  ENST00000381373 UHRF2-002 6413418-6422979 protein_coding
  ENST00000450508 UHRF2-004 6421031-6477654 protein_coding
  ENST00000461236 UHRF2-013 6414058-6434025 processed_transcript
  ENST00000468435 UHRF2-001 6413151-6507054 nonsense_mediated_decay
  ENST00000469298 UHRF2-011 6413193-6434348 processed_transcript
  ENST00000477183 UHRF2-007 6482051-6492844 processed_transcript
  ENST00000479000 UHRF2-008 6497049-6498150 processed_transcript
  ENST00000481049 UHRF2-012 6413777-6460581 processed_transcript
  ENST00000481243 UHRF2-009 6504350-6506112 processed_transcript
  ENST00000484159 UHRF2-010 6434088-6495998 retained_intron
  ENST00000485617 UHRF2-005 6486871-6507054 processed_transcript
  ENST00000492853 UHRF2-006 6498352-6507054 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000276893ENST00000450508ENST00000468435ENST00000484159ENST00000485617ENST00000492853
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000276893 2.964±0.00 3.229±0.00 1.746±0.00 1.804±0.90 3.079±0.46 5.264±4.02 1.299±1.01 5.637±0.00 2.190±0.95 4.059±1.40 2.568±1.98 4.670±1.10 3.829±0.98 7.449±0.00
ENST00000450508 N/A N/A 8.354±0.00 N/A N/A N/A N/A N/A N/A N/A 3.029±0.00 N/A N/A N/A
ENST00000468435 N/A N/A N/A 1.164±0.00 N/A N/A N/A N/A N/A N/A N/A 1.939±0.00 0.611±0.00 3.910±1.82
ENST00000484159 N/A 1.393±0.00 1.025±0.00 0.904±0.00 2.949±0.00 N/A 0.350±0.01 1.098±0.00 N/A 2.678±0.00 0.287±0.00 1.338±0.00 N/A N/A
ENST00000485617 N/A N/A N/A 0.826±0.00 0.604±0.00 N/A 0.362±0.00 1.266±0.00 N/A N/A 0.603±0.00 1.663±0.38 N/A N/A
ENST00000492853 N/A 2.312±0.00 N/A 0.947±0.00 N/A N/A N/A 1.427±0.00 0.390±0.00 N/A N/A 2.209±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001D5 CIL_0001D5_0001 CGP 9:6328375-6507054
CIL_0001D8 CIL_0001D8_0001 CGP 9:6413151-6645650

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003677 IEA DNA binding
GO:0004842 IDA ubiquitin-protein transferase activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005720 ISS nuclear heterochromatin
GO:0006511 IDA ubiquitin-dependent protein catabolic process
GO:0007049 IEA cell cycle
GO:0008270 IEA zinc ion binding
GO:0008283 IEP cell proliferation
GO:0016567 IDA protein ubiquitination
GO:0016874 IEA ligase activity
GO:0030154 IEP cell differentiation
GO:0042393 ISS:IEA histone binding
GO:0051726 TAS regulation of cell cycle
GO:0051865 IDA protein autoubiquitination
GO:0071158 IDA positive regulation of cell cycle arrest

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000089389 CABZ01073380.1 Uncharacterized protein protein_coding Danio_rerio
ENSDARG00000089654 UHRF2 (2 of 2) ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase protein_coding Danio_rerio
ENSDARG00000090666 ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase protein_coding Danio_rerio
ENSMUSG00000024817 Uhrf2 ubiquitin-like, containing PHD and RING finger domains 2 protein_coding Mus_musculus

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